Evidence map›Paper›PMID 41388768›Full record

ArticlePharmaceutical biology2026

Graveoumarins A-C: chiral resolution, absolute configuration, and anticoagulant/anti-inflammatory activities of 3'-methyl-3'-butenyl coumarins from

Zhihao Wu, Xiaolin Liao, Yuxin Wang, Jian Yin, Xu Feng, Lingfei Tong, Hao Huang, Yueping Jiang, Xiongjun Hou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhihao WuDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, China.
Xiaolin LiaoDepartment of Clinical Pharmacy, Hunan University of Medicine General Hospital, Huaihua, Hunan, China.
Yuxin WangDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, China.
Jian YinDepartment of Clinical Pharmacy, Hunan University of Medicine General Hospital, Huaihua, Hunan, China.
Xu FengDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, China.
Lingfei TongDepartment of Pharmacy, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China.
Hao HuangJiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine, School of Pharmacy, Gannan Medical University, Ganzhou, China.
Yueping JiangDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, China.
Xiongjun HouDepartment of Pharmacy, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextSeveral coumarins have been isolated from

objectiveThis study aimed to comprehensively separate and characterize the chirality of 3'-methyl-3'-butenylcoumarins from MATERIALS AND

methodsComprehensive chromatographic separation and chiral HPLC analysis were employed on the

resultsThe study led to the isolation of two pairs of enantiomeric 3'-methyl-3'-butenylcoumarins, present in both equivalent and inequivalent ratios. This included two previously undescribed chiral 3'-methyl-3'-butenylcoumarins with specific absolute configurations [(+)-2'

conclusionsThis study successfully characterized the chirality and determined the absolute configurations of specific 3'-methyl-3'-butenylcoumarins from

Indexed as

AnticoagulantsAnti-Inflammatory AgentsCoumarinsPlant ExtractsRutaAnimalsChromatography, High Pressure LiquidLipopolysaccharidesMacrophagesMiceNitric OxideRAW 264.7 CellsStereoisomerismAnticoagulantsAnti-Inflammatory AgentsCoumarinsLipopolysaccharidesNitric OxidePlant Extractsabsolute configurationsactivity evaluationchiral HPLC resolutionenantiomeric coumarinsRuta graveolens L

Identifiers

PMID41388768
PMCPMC12704130

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.