Evidence map›Paper›PMID 41389132›Full record

ReviewPediatric cardiology2026

Enhancing Cardiopulmonary Exercise Testing in Complex Congenital Heart Disease: The Role of Spirometry, Body Composition, and Handgrip Strength.

Alan P Wang, Clara Garcia, Dylan Schellenberg, Garett J Griffith, Kendra Ward

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alan P WangDivision of Pediatric Cardiology, Mayo Clinic, 200 1 st Street SW, Rochester, MN, 55905, USA. Wang.alan@mayo.edu.
Clara GarciaDivision of Pediatric Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E. Chicago Avenue, Chicago, IL, 60611, USA.
Dylan SchellenbergDivision of Pediatric Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E. Chicago Avenue, Chicago, IL, 60611, USA.
Garett J GriffithNorthwestern University Department of Physical Therapy and Human Movement Sciences, 645 N. Michigan Ave., Suite 1100, Chicago, 60611, USA.
Kendra WardDivision of Pediatric Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E. Chicago Avenue, Chicago, IL, 60611, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiopulmonary exercise testing (CPET) is a cornerstone of functional assessment in congenital heart disease (CHD), yet there are additional important contributors to exercise limitation that are not directly measured by CPET. This narrative review highlights the complementary utility of spirometry, body composition analysis, and evaluation of handgrip strength in augmenting our understanding of functional capacity in CHD. Spirometry provides insights into restrictive lung disease patterns prevalent in post-surgical CHD populations; body composition analysis, especially lean mass assessment, can reveal sarcopenia not apparent using BMI alone; and handgrip strength serves as a validated surrogate for overall muscular function and frailty. We propose routine integration of all three testing techniques as complements to CPET protocols to enhance clinical assessment, guide rehabilitation, and support prognostication in pediatric CHD patients. This review advocates for broader adoption and standardization of these measures in clinical settings to improve risk stratification and long-term outcomes.

Indexed as

Body CompositionExercise TestHand StrengthHeart Defects, CongenitalSpirometryChildExercise ToleranceHumansBioelectrical impedance analysisBody composition analysisCardiopulmonary exercise testingDual-energy x-ray absorptiometryExercise capacityHandgrip strengthPediatricSpirometry

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.