Evidence map›Paper›PMID 41389355›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2026

Therapeutic Footwear for Medial Knee Osteoarthritis: Individualizing Midsole Stiffness Enhances Intended Kinetic Changes.

Baptiste Ulrich-Ischer, Alexis Cantaloube, Laurent Hoffmann, Brigitte M Jolles, Julien Favre

Abstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Therapeutic Footwear for Medial Knee Osteoarthritis: Individualizing Midsole Stiffness Enhances Intended Kinetic Changes.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Baptiste Ulrich-IscherDepartment of Orthopedic Surgery and Traumatology, Lausanne University Hospital and University of Lausanne (CHUV-UNIL), Lausanne, Switzerland.ORCID 0000-0003-4005-0806
Alexis CantaloubeDepartment of Orthopedic Surgery and Traumatology, Lausanne University Hospital and University of Lausanne (CHUV-UNIL), Lausanne, Switzerland.
Laurent HoffmannNUMO Orthopedic Systems, Dietikon, Switzerland.
Brigitte M JollesDepartment of Orthopedic Surgery and Traumatology, Lausanne University Hospital and University of Lausanne (CHUV-UNIL), Lausanne, Switzerland.
Julien FavreDepartment of Orthopedic Surgery and Traumatology, Lausanne University Hospital and University of Lausanne (CHUV-UNIL), Lausanne, Switzerland.

Funding

This study was partially funded by the Swiss National Science Foundation (SNSF Grant #32003B-166433) and the Lausanne Orthopedic Research Foundation.
6 · The paper itself

Abstract

Progression of medial knee osteoarthritis (OA) has been associated with walking biomechanics, specifically with the knee adduction (KAM) and flexion (KFM) moments. Lower medial stiffness shoes (LMSS), that are shoes with the sole made of softer material medially than laterally, were proposed for disease management through KAM reductions. This study primarily tested the hypothesis that larger pKAM reductions can be achieved with stiffness ratios selected individually than with the smallest ratios of the LMSS. Secondarily, the proportions of individuals reducing the KAM or reducing the KAM without increasing the KFM were compared between the individualized and smallest ratios conditions. The two LMSS conditions were also compared with lateral wedge insoles. Walking biomechanics were recorded for 15 OA patients (8 males; 62.3 ± 9.6 years old) and 14 asymptomatic individuals (5 males; 53.6 ± 3.6 years old) wearing LMSS with various stiffness ratios and wedges. Larger decreases in KAM were obtained with individualized stiffness ratios (14.0%-16.4%) than with the two other interventions (6.7%-12.5%) (p < 0.001). The percentage of participants reducing the KAM without increasing the KFM was larger with individualized ratios compared to the smallest ratios in the OA group (14 vs. 6; p = 0.001) and compared to wedges in the asymptomatic group (13 vs. 6; p = 0.015). This exploratory study showed the potential of individualizing the stiffness ratios, particularly in terms of KAM reduction amplitude, percentage of individuals achieving specific modifications, and possibility to aim for more complex kinetic changes. Further work is necessary to assess the effect of individualized stiffness ratios on clinical outcomes.

Indexed as

Foot OrthosesOsteoarthritis, KneeShoesAgedBiomechanical PhenomenaFemaleHumansMaleMiddle AgedWalkinggaitkinematics and kineticskneeosteoarthritisrehabilitation

Identifiers

PMID41389355
PMCPMC12701722

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.