Evidence map›Paper›PMID 41390907›Full record

ArticleInternational journal of obesity (2005)2026

Waist-to-height ratio as a non-invasive marker of renal sinus fat: a MRI-based cohort study.

Diego Moriconi, Miikka-Juhani Honka, Ekaterina Saukko, Emilia Moritz, Aino Latva-Rasku, Prince Dadson, Nelli Tuomola, Laura Pekkarinen, Paulina Salminen, Pirjo Nuutila and 1 more

Abstract read
In one paragraph

Article in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Diego MoriconiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Miikka-Juhani HonkaTurku PET Centre, University of Turku, Turku, Finland.
Ekaterina SaukkoDepartment of Radiology, Turku University Hospital, Turku, Finland.
Emilia MoritzTurku PET Centre, University of Turku, Turku, Finland.
Aino Latva-RaskuTurku PET Centre, University of Turku, Turku, Finland.
Prince DadsonTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0001-5063-304X
Nelli TuomolaTurku PET Centre, University of Turku, Turku, Finland.ORCID 0009-0006-9004-4200
Laura PekkarinenTurku PET Centre, University of Turku, Turku, Finland.
Paulina SalminenDivision of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.ORCID 0000-0001-6435-9264
Pirjo NuutilaTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0001-9597-338X
Eleni RebelosDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy. eleni.rebelos@utu.fi.ORCID 0000-0003-3050-8692

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsRenal sinus fat (RSF) is an ectopic fat depot whose expansion has been linked to hypertension and chronic kidney disease. We assessed a range of adiposity indices to determine whether they offer more accurate predictions of RSF than BMI. METHODS AND

resultsRenal sinus fat (RSF) and RSF relative to total kidney area (RSF%) were assessed via MRI in 74 individuals with severe obesity and 47 lean volunteers. 50 persons with obesity were re-evaluated 6 to 12 months after undergoing bariatric surgery. In multivariable regression analyses adjusted for age, sex, and BMI, the Body Roundness Index (BRI), waist-to-height ratio (WHtR), and waist circumference showed the strongest associations with RSF. Of these, only WHtR was significantly associated with RSF%. In univariate analyses, both RSF and RSF% were inversely correlated with estimated glomerular filtration rate (eGFR); however, in multivariate analysis, only RSF% remained independently associated with eGFR. Post-bariatric surgery, RSF change correlated with changes in WHtR and BRI.

conclusionAdiposity measures incorporating waist circumference are associated with RSF independent of BMI. While RSF exhibits a stronger relationship with adiposity measures, RSF% predicts eGFR. Both metrics offer complementary insights and should be considered in future studies.

Indexed as

AdiposityKidneyObesity, MorbidWaist-Height RatioAdultBariatric SurgeryBiomarkersBody Mass IndexCohort StudiesFemaleGlomerular Filtration RateHumansMagnetic Resonance ImagingMaleMiddle AgedWaist CircumferenceBiomarkers

Identifiers

PMID41390907
PMCPMC12965879

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.