Evidence map›Paper›PMID 41391019›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

WDR5-H3K4me3 Epigenetic Axis Promotes TRMT6-Dependent tRNA M

Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou and 3 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuqing LeiDepartment of Molecular Pathology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, 450008, China.
Xue WangDepartment of Medical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Jiahe LiuDepartment of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Zixu NiuDepartment of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Jiaqi HuaDepartment of Medical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Qian GuoDepartment of Rhinology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Dan DuDepartment of Medical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Yuanchang ZhuDepartment of Gastroenterology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Fucheng HeDepartment of Medical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Mingxia ZhouDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Hongle LiDepartment of Molecular Pathology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, 450008, China.
Jing HeDepartment of Breast Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Jun LiDepartment of Molecular Pathology, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, 450008, China.

Funding

Henan Province Young and Middle-aged Health Science and Technology Innovation Talent Project YQRC2025005Henan Province Young and Middle-aged Health Science and Technology Innovation Talent Project YQRC2025012Henan Provincial Key Scientific and Technological Project 242102311020Henan Provincial Key Scientific and Technological Project 242102311035Henan Provincial Key Scientific and Technological Project 242301420065Henan Provincial Key Scientific and Technological Project 252102310046National Natural Science Foundation of China 82203332National Natural Science Foundation of China 82272417National Natural Science Foundation of China 82300606National Natural Science Foundation of China 82573924Natural Science Foundation of Henan 252300421114
6 · The paper itself

Abstract

N

Indexed as

Epigenesis, GeneticFerroptosisHistone-Lysine N-MethyltransferaseHistonesRNA, TransferTriple Negative Breast NeoplasmstRNA MethyltransferasesCell Line, TumorDisease ProgressionFemaleFerritinsGene Expression Regulation, NeoplasticHumansMethylationOxidoreductasesFerritinsFTH1 protein, humanhistone H3 trimethyl Lys4Histone-Lysine N-MethyltransferaseHistonesOxidoreductasesRNA, TransfertRNA MethyltransferasesferroptosisN1‐methyladenosineTNBCTRMT6WDR5

Identifiers

PMID41391019
PMCPMC12931253

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.