Evidence map›Paper›PMID 41392256›Full record

ReviewBiotechnology for biofuels and bioproducts2025

Sophorolipids: multifunctional microbial glycolipids with diverse bioactivities and applications.

Chaozhi Wang, Chunyang Zhou, Yazheng Cao, Mohd Sadeeq, Ke Yu, Feifei Hou, Peng Xiong

Abstract readReview
In one paragraph

Review in Biotechnology for biofuels and bioproducts, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chaozhi WangSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo, 255000, China.
Chunyang ZhouSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo, 255000, China.
Yazheng CaoSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo, 255000, China.
Mohd SadeeqSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo, 255000, China.
Ke YuSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo, 255000, China.
Feifei HouSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo, 255000, China. houff@sdut.edu.cn.
Peng XiongSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo, 255000, China. xiongp@sdut.edu.cn.

Funding

Natural Science Foundation of Shandong Province, China ZR2024QC398Scientific Research Starting Foundation of Shandong University of Technology 4041/422046
6 · The paper itself

Abstract

Sophorolipids (SLs) are glycolipid biosurfactants produced by non-pathogenic yeasts and represent a sustainable, biocompatible alternative to synthetic surfactants. Their amphiphilic architecture-comprising a hydrophilic sophorose headgroup and a hydrophobic fatty acid tail-confers excellent surface activity, emulsifying capacity, and a broad spectrum of biological effects. This review synthesizes advances since 2020 in understanding SL bioactivities, including antibacterial, antifungal, antibiofilm, antiviral, anti-inflammatory, antioxidant, and anticancer effects. We examine structure-activity relationships that govern functionality and survey strategies to enhance efficacy, such as chemical modification to generate novel derivatives and incorporation into nanostructures for targeted delivery. The review also evaluates application potential across sectors-agriculture (biopesticides, soil amendments), food (emulsifiers, preservatives), healthcare (therapeutics, coatings), and environmental remediation (oil and heavy-metal removal). Despite promising developments, challenges remain in production scaling, mechanistic clarity, and comprehensive characterization of novel SL. Addressing these issues will facilitate the integration of SLs into sustainable, high-value bioproducts aligned with green chemistry principles.

Indexed as

ApplicationsBioactivitiesBiosurfactantPropertiesSophorolipids

Identifiers

PMID41392256
PMCPMC12821877

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.