ReviewEmerging microbes & infections2026
Mpox animal models: a comprehensive evaluation of susceptible species for pathogenesis studies and drug discovery.
Review in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Mpox, formerly known as monkeypox, has shifted from a regional concern to a global health priority. Progress toward targeted antivirals and vaccines, however, still hinges on a complex array of animal models developed over the last sixty years. This review distills all literature regarding Mpox animal models - from rodent to non-human primate species - into a clear, comparative narrative. We outline how host species, viral clade, and inoculation route shape clinical course and immune responses, and we identify which models best address questions of pathogenesis, transmission, and medical countermeasure efficacy. The resulting roadmap is designed to help researchers, funders, and regulators select the most informative tools and streamline mpox drug discovery pipelines.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.