ArticleFrontiers in cardiovascular medicine2025
Comparison of multiple machine learning methods for predicting postoperative hyperglycemia in patients without diabetes undergoing cardiac surgery.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Stress-induced hyperglycemia (SHG) represents a significant metabolic complication in non-diabetic cardiac surgery older adult patients, with substantial implications for postoperative outcomes. Despite its clinical importance, reliable predictive tools remain scarce. This study systematically compared the performance of logistic regression 5 s. advanced machine learning algorithms for SHG risk prediction in this vulnerable population. Patients and Methods: We conducted a retrospective cohort analysis of 600 patients (≥65 years) undergoing cardiac surgery at a tertiary medical center (January 2021-May 2025). Six clinically relevant perioperative variables were incorporated into five predictive models: logistic regression, Random Forest (RF), Gradient Boosting Machine (GBM), Adaptive Boosting (AdaBoost), and Extreme Gradient Boosting (XGBoost). Model performance was rigorously evaluated using AUC-ROC with 95% confidence intervals, sensitivity, specificity, positive (PPV) and negative predictive values (NPV), and precision. Results: The incidence of SHG in this cohort was 70.5%. Comparative analysis revealed logistic regression as the top-performing model (AUC 0.944, 95% CI 0.923-0.966), surpassing other algorithms: GBM (0.923, 0.902-0.952), 10GBoost (0.904, 0.890-0.941), AdaBoost (0.916, 0.871-0.936), and RF (0.877, 0.866-0.932). Moreover, the logistic model achieved optimal performance in sensitivity (94.5%), specificity (93.4%), PPV (97.7%), and NPV (96.8%). Conclusion: In contrast to more complex machine learning approaches, logistic regression demonstrated superior predictive accuracy for SHG in non-diabetic cardiac surgery older adult patients. Its exceptional performance metrics and clinical interpretability support its practical utility as an effective decision-support tool for perioperative risk stratification and management.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.