SynthesisFrontiers in surgery2025
Association between Modic changes and recurrence of lumbar disc herniation after percutaneous endoscopic lumbar discectomy: a meta-analysis.
Synthesis in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Construction and Validation of a Nomogram Prediction Model for Recurrent Lumbar Disc Herniation After Percutaneous Endoscopic Lumbar Discectomy.Risk management and healthcare policy · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aims to identify the association between preoperative Modic changes and the recurrence of lumbar disc herniation (LDH) in patients who have undergone percutaneous endoscopic lumbar discectomy (PELD). Methods: The PubMed, Web of Science, EMBASE, and CNKI databases were searched from their inception until 19 March 2025. Early recurrence was defined as herniation occurring within 6 months postoperatively, whereas late recurrence referred to herniation occurring after 12 months. Odds ratios (ORs) with 95% confidence intervals (CIs) were combined, and subgroup analyses were conducted according to the recurrence type. Results: Twenty-seven studies involving 10,116 patients were included, with the majority of studies originating from China (25/27). The recurrence rates for patients without and with Modic changes were 7.44% and 16.41%, respectively (type I: 15.01%; type II/III: 18.14%; Conclusion: Preoperative Modic changes are associated with postoperative recurrence among LDH patients undergoing PELD, and the presence of Modic changes is related to a significantly higher risk of early and late recurrence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.