ArticlePakistan journal of medical sciences2025
Prognostic significance of systemic immune inflammation index and systemic inflammation response index for cervical cancer: A systematic review and meta-analysis.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Additional predictive value of systemic inflammation indices beyond prostate specific antigen density for clinically significant prostate cancer.BMC urology · 2026Article
- Prognostic value of an integrated immune-inflammatory phenotype in surgically treated cervical cancer: survival modeling and immunohistochemical validation.Frontiers in immunology · 2026Article
- Systemic Inflammatory Indices-Systemic Immune-Inflammation Index (SII) and the Systemic Inflammation Response Index (SIRI)-As Potential Rule-Out Biomarkers for Invasive Cervical Carcinoma.International journal of molecular sciences · 2025Observational
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: We present the first systematic review and meta-analysis examining the association between systemic immune inflammation index (SII) and systemic inflammation response index (SIRI) for predicting prognosis of cervical cancer. Methodology: Cochrane CENTRAL library, Embase, Medline (PubMed), Scopus and Web of Science databases were explored up to 25 Results: We included 13 studies with 15 cohorts. We noted that high SII scores were associated with statistically significant increased risk of poor OS (HR: 2.15 95% CI: 1.48, 3.14 I Conclusions: SII can be used to predict OS and DFS in cervical cancer. However, SIRI was found to predict only OS and not DFS with less robust results. Further studies shall provide better evidence.
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Registered trials
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