Evidence map›Paper›PMID 41394485›Full record

ReviewBiomedical optics express2025

Review of dynamic optical coherence tomography for intracellular motility: signals, metrics, and their applications [Invited].

Amy L Josefsberg, Lin Yang, Taylor N Robinson

Erratum issuedAbstract readReview
In one paragraph

Review in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Amy L JosefsbergDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID https://orcid.org/0000-0002-2642-8350
Lin YangDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Taylor N RobinsonDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Funding

Developing an in vitro to in vivo pipeline of mammary gland exposure-response relationships to per- and poly-fluoroalkyl substances (PFAS)R01ES032730 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LOCKETT, MATTHEW RYEN, OLDENBURG, AMY L · 2020 to 2024
$2.6M
NIEHS NIH HHS R01 ES032730
6 · The paper itself

Abstract

Dynamic optical coherence tomography (dOCT) is a group of techniques primarily applied to visualize intracellular motility within tissue biopsies and cultures as it relates to changes in cell viability, status, and stiffness. Here, we provide an overview of variance-based, autocorrelation-based, and spectral algorithms commonly applied to different types of dOCT signals, how the metrics extracted using these algorithms relate to the underlying intracellular motion, and review how they have been employed in dOCT applications. Detailed guidance is provided for selecting or developing metrics and algorithms to use, depending on the OCT hardware and biological motions of interest.

Identifiers

PMID41394485
PMCPMC12698081

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.