Evidence map›Paper›PMID 41395241›Full record

ReviewTransboundary and emerging diseases2025

Nanoparticle-Based Antiviral Vaccines for Chickens: Recent Advances and Future Perspectives.

Peiyang Ding, Litong Xia, Shuoqi Dong

Abstract readReview
In one paragraph

Review in Transboundary and emerging diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Peiyang DingSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China, zzu.edu.cn.ORCID https://orcid.org/0000-0001-6332-8597
Litong XiaSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China, zzu.edu.cn.ORCID https://orcid.org/0009-0008-2192-2908
Shuoqi DongSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China, zzu.edu.cn.ORCID https://orcid.org/0009-0007-2964-1265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral diseases in chickens, such as avian influenza, Newcastle disease, and infectious bronchitis, cause significant economic losses to the global chicken industry, while the cross-species transmission risks of avian influenza viruses (AIVs) pose potential threats to public health security. Conventional inactivated vaccines and live attenuated vaccines exhibit limitations in terms of protective coverage, immunization duration, and safety profiles, necessitating the development of novel vaccine strategies. In recent years, the application of nanotechnology has been bringing new opportunities for chicken vaccine development. As innovative vaccine carriers, nanoparticles demonstrate unique advantages through their size effects, surface modifiability, and antigen-loading capacity, enabling precise regulation of antigen delivery efficiency and enhance innate immune responses via activation of pattern recognition receptors. This review summarizes recent advancements in nanoparticle-based vaccines for chickens, with particular emphasis on nanocarrier design principles, immunological mechanisms, and protective efficacy. The potential of these systems to improve immune responses and extend protective duration is systematically analyzed, with future research priorities outlined to guide the development of next-generation chicken vaccines.

Indexed as

ChickensInfluenza in BirdsNanoparticlesPoultry DiseasesViral VaccinesAnimalsViral Vaccineschicken vaccinesimmune mechanismsnanotechnologyviral diseases

Identifiers

PMID41395241
PMCPMC12697807

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.