Evidence map›Paper›PMID 41395269›Full record

ArticleFrontiers in neuroscience2025

taVNS as a potential countermeasure for neurocognitive decline in microgravity.

L Fricke, C Wienke, T Zaehle

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

L FrickeMedical Faculty, Institute of Medical Psychology, Otto-von-Guericke University of Magdeburg, Magdeburg, Germany.
C WienkeResearch Group "Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen" (MARS), Otto-von-Guericke-University of Magdeburg, Magdeburg, Germany.
T ZaehleMedical Faculty, Institute of Medical Psychology, Otto-von-Guericke University of Magdeburg, Magdeburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to microgravity induces significant physiological, cognitive, and psychomotor changes in the human body. While countermeasures such as resistance exercise and cardiovascular conditioning have been developed to address musculoskeletal and circulatory issues, there remains a critical gap in mitigating neurophysiological and cognitive deficits caused by microgravity. Transcutaneous auricular vagus nerve stimulation (taVNS) is a non-invasive neuromodulation technique that promises to enhance psychomotor function, and cognitive performance in microgravity as well as on Earth. This article examines the challenges of spaceflight, particularly cognitive impairments and related psychomotor dysfunction, and explores the potential application of taVNS in space. The neurophysiological mechanisms underlying microgravity-related decline and the proposed mechanism of action of taVNS are discussed, focusing on its effects on neuroplasticity, autonomic regulation, and sensorimotor integration. taVNS emerges as a promising countermeasure to mitigate neuropsychological impairments associated with exposure to microgravity.

Indexed as

cognitive impairmentsmicrogravityparabolic flightspace medicinetaVNS

Identifiers

PMID41395269
PMCPMC12695850

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.