Evidence map›Paper›PMID 41395603›Full record

ReviewFrontiers in oncology2025

Advances in colorectal cancer screening: technological innovations, guideline discrepancies, and individualized strategies.

Li Tang, Xiaoyong Zhao, Guohong Wang, Jiehao Huang, Mu Zhang, Wei Xu

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Beyond the biopsy: the new era of non-invasive staging and biomarkers in colorectal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Li Tang *Department of Anesthesiology, the First Affiliated Hospital, Yangtze University, Jingzhou, Hubei, China.
Xiaoyong Zhao *Department of Anesthesiology, the First Affiliated Hospital, Yangtze University, Jingzhou, Hubei, China.
Guohong WangDepartment of Anesthesiology, the First Affiliated Hospital, Yangtze University, Jingzhou, Hubei, China.
Jiehao HuangDepartment of Ultrasound, the First Affiliated Hospital, Yangtze University, Jingzhou, Hubei, China.
Mu ZhangDepartment of Anesthesiology, the First Affiliated Hospital, Yangtze University, Jingzhou, Hubei, China.
Wei XuDepartment of Anesthesiology, the First Affiliated Hospital, Yangtze University, Jingzhou, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide. Numerous clinical and epidemiological studies have demonstrated that early screening can significantly reduce both the incidence and mortality of CRC. This review systematically summarizes recent advances in CRC screening technologies. It first reviews the current applications of traditional screening tools such as colonoscopy and fecal occult blood tests, then focuses on emerging molecular detection techniques based on DNA, RNA, proteins, and metabolites, as well as representative multi-omics integration approaches. Furthermore, it discusses the innovative use of artificial intelligence (AI) and image recognition technologies in CRC screening. At the guideline level, we compare recent updates and implementation differences among major national screening guidelines, including those of the U.S. Preventive Services Task Force (USPSTF), and analyze key challenges in current screening practices. Finally, we propose directions for future development. By integrating existing evidence, this review aims to provide clinical reference for transforming CRC screening from population-based to precision-based individualized prevention, promoting its wide, efficient, and sustainable implementation.

Indexed as

artificial intelligencecolorectal cancerEarly detectionguideline discrepanciesMolecular diagnosticsScreening technology

Identifiers

PMID41395603
PMCPMC12698480

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.