Evidence map›Paper›PMID 41396156›Full record

ArticleeLife2025

Dissociable memory modulation mechanisms facilitate fear amnesia at different timescales.

Yinmei Ni, Ye Wang, Zijian Zhu, Jingchu Hu, Daniela Schiller, Jian Li

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yinmei Ni *School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China.ORCID https://orcid.org/0000-0003-3614-1828
Ye Wang *School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China.
Zijian ZhuSchool of Psychology, Shaanxi Normal University, Xi'an, China.
Jingchu HuDepartment of Anxiety Disorders, Shenzhen Kangning Hospital, Shenzhen Mental Health Institute, Shenzhen, China.
Daniela SchillerDepartments of Psychiatry and Neuroscience, and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID https://orcid.org/0000-0002-0357-7724
Jian LiSchool of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China.ORCID https://orcid.org/0000-0002-3941-2622

Funding

Neurocomputational mechanisms of proactive social behavior deficits in autism spectrum disorderR01MH122611 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FOSS-FEIG, JENNIFER, GU, XIAOSI · 2020 to 2024
$3.9M
Neural, computational and behavioral characterization of dynamic social behavior in borderline and avoidant personality disorderR01MH123069 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GU, XIAOSI, KOENIGSBERG, HAROLD W · 2021 to 2025
$3.1M
National Natural Science Foundation of China 32071090National Natural Science Foundation of China 32441111National Science and Technology Major Project 2021ZD0203702NIMH NIH HHS R01 MH122611NIMH NIH HHS R01MH122611NIMH NIH HHS R01 MH123069NIMH NIH HHS R01MH123069
6 · The paper itself

Abstract

Memory reactivation renders consolidated memory fragile and thereby opens the window for memory updates, such as memory reconsolidation. However, whether memory retrieval facilitates update mechanisms other than memory reconsolidation remains unclear. We tested this hypothesis in three experiments with healthy human participants. First, we demonstrate that memory retrieval-extinction protocol prevents the return of fear expression shortly after extinction training, and this short-term effect is memory reactivation dependent (Study 1,

Indexed as

AmnesiaFearMemoryMental RecallAdultCuesExtinction, PsychologicalFemaleHumansMalePrefrontal CortexTime FactorsYoung AdultamnesiacTBSdlPFCfear memoryhumanmemory retrievalneurosciencereconsolidation

Identifiers

PMID41396156
PMCPMC12705067

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.