Evidence map›Paper›PMID 41396338›Full record

ReviewCurrent pain and headache reports2025

Efficacy and Safety of Sphenopalatine Ganglion Blocks to Treat Head and Neck Cancer-Related Pain: A Narrative Review.

Van S Smith, Se Yun Cheon, Shahab Ahmadzadeh, Caroline R Burroughs, Aiden B De Witt, Patricia Griffin, Sahar Shekoohi, Alaa Abd-Elsayed, Alan D Kaye

Abstract readReview
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In one paragraph

Review in Current pain and headache reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Van S SmithSchool of Medicine, Louisiana State University Health Shreveport, Shreveport, LA, 71103, USA.
Se Yun CheonTulane University School of Medicine, New Orleans, LA, 70112, USA.
Shahab AhmadzadehDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Caroline R BurroughsDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Aiden B De WittDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Patricia GriffinDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
Sahar ShekoohiDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA. sahar.shekoohi@lsuhs.edu.
Alaa Abd-ElsayedDepartment of Anesthesiology, University of Wisconsin, Madison, WI, USA.
Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewCancer is a devastating disease that affects many people across the world. Cancer has a variety of different locations and body systems it can affect, making it a complex disease to manage at times, especially when dealing with cancer of the head and neck. RECENT

findingsPatients suffering from this disease can experience significant levels of pain, and it is made worse by the treatments for the disease, causing additional pain. Sphenopalatine ganglion blocks are a form of pain management observed in head and neck cancer treatment. This technique aims to disrupt the signaling pathways of the sphenopalatine ganglion and serve as an efficient, minimally invasive form of acute pain management. In this review, we will discuss the pathophysiology of head and neck cancer-related pain, the details of the sphenopalatine ganglion block, and its efficacy in clinical use, particularly with head and neck cancer patients.

Indexed as

Cancer PainHead and Neck NeoplasmsPain ManagementSphenopalatine Ganglion BlockHumansTreatment OutcomeCancerHeadInterventional painNeckSphenopalatine ganglion blocks

Identifiers

PMID41396338

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.