Evidence map›Paper›PMID 41396368›Full record

ArticleMolecular biomedicine2025

Th-1 cytokine-primed small extracellular vesicles from limbal mesenchymal stem cells modulate immune and inflammatory responses in Hashimoto's Thyroiditis: an ex vivo proof-of-concept study.

Laura Tomasello, Valentina Guarnotta, Giuseppe Siragusa, Mattia Biondo, Giorgio Arnaldi, Carla Giordano, Giuseppe Pizzolanti

Abstract readLetter
In one paragraph

Article in Molecular biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laura TomaselloDepartment of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties, Laboratory of Endocrinology and Regenerative Medicine "Aldo Galluzzo", University of Palermo, Piazza Delle Cliniche 2, Palermo, 90127, Italy.ORCID http://orcid.org/0000-0002-2304-6007
Valentina GuarnottaDepartment of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties, Laboratory of Endocrinology and Regenerative Medicine "Aldo Galluzzo", University of Palermo, Piazza Delle Cliniche 2, Palermo, 90127, Italy. valentina.guarnotta@unipa.it.ORCID http://orcid.org/0000-0002-8088-4947
Giuseppe SiragusaUniversity Hospital "Paolo Giaccone", Piazza Delle Cliniche 2, Palermo, 90127, Italy.ORCID http://orcid.org/0009-0007-4734-0773
Mattia BiondoScienze E Tecnologie Biologiche Chimiche E Farmaceutiche (STEBICEF), University of Palermo, Viale Delle Scienze, Ed. 16, Palermo, 90128, Italy.ORCID http://orcid.org/0009-0002-6880-2192
Giorgio ArnaldiDepartment of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties, Laboratory of Endocrinology and Regenerative Medicine "Aldo Galluzzo", University of Palermo, Piazza Delle Cliniche 2, Palermo, 90127, Italy.ORCID http://orcid.org/0000-0002-6204-3423
Carla GiordanoDepartment of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties, Laboratory of Endocrinology and Regenerative Medicine "Aldo Galluzzo", University of Palermo, Piazza Delle Cliniche 2, Palermo, 90127, Italy.ORCID http://orcid.org/0000-0003-1731-9395
Giuseppe PizzolantiDepartment of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties, Laboratory of Endocrinology and Regenerative Medicine "Aldo Galluzzo", University of Palermo, Piazza Delle Cliniche 2, Palermo, 90127, Italy.ORCID http://orcid.org/0000-0001-6052-8438

Funding

PNRR M4C2I1.3 Samothrace PRJ-1103
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41396368
PMCPMC12705507

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.