Evidence map›Paper›PMID 41396390›Full record

ArticleRice (New York, N.Y.)2025

OsSSID6 Negatively Regulates Salt Stress Tolerance in Rice (Oryza Sativa L.) via Metabolic Pathways and ROS Scavenging.

Ziyi Wang, Xiaofei Zan, Hao Chen, Jiali Zhu, Xiulin Zhao, Mingfei Chen, Yijuan Kong, Juan Yang, Xiaomei Jia, Xiaoying Ye and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Rice (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ziyi Wang *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Xiaofei Zan *State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Hao ChenState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Jiali ZhuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Xiulin ZhaoState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Mingfei ChenState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Yijuan KongState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Juan YangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Xiaomei JiaState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Xiaoying YeState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Chuanqiang LiuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Rongjun ChenState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Jianqing ZhuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Jun ZhuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Lihua LiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute, Sichuan Agricultural University, Chengdu, 611130, China. lilihua1976@sicau.edu.cn.

Funding

Sichuan Provincial Science and Technology Support Program 2022ZDZX0012
6 · The paper itself

Abstract

Soil salinization is becoming a huge threat to reducing productivity of rice (Oryza sativa L.) around the world. Previous studies have found that some Domain of unknown function (DUF) proteins play an essential role in the growth and development of plants. The DUF936 family is reported to respond to abiotic stresses, but the specific molecular mechanisms of its members remain elusive. In this study, OsSSID6 (Salt-Stress Induced DUF936 protein) is found at the cell membrane and the protein's expression could be affected by several abiotic stresses. The CRISPR/Cas9 knockout lines increased salt tolerance in rice, whereas the overexpression lines showed more sensitivity. And meanwhile the similar changes of ROS-scavenging capacity were observed both in knockout and overexpression lines. Transcriptome analysis identified that the expression of genes linked to multiple metabolic pathways, including phenylpropanoid and flavonoid biosynthesis, and stress response, was significantly up-regulated in KO lines. Our findings reveal that OsSSID6 gene modulates rice salt stress tolerance by orchestrating a network of metabolic pathways, including those involved in the reactive oxygen species (ROS) scavenging system, phenylpropanoid and flavonoid biosynthesis and stress response-related mechanism. sThese results provide important information for engineering salt-tolerant crops.

Indexed as

DUFRiceROSSalt stressTranscriptome analysis

Identifiers

PMID41396390
PMCPMC12705515

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.