Evidence map›Paper›PMID 41397565›Full record

ReviewExperimental hematology2026

Hematopoietic stem cell-independent and -dependent hematopoiesis: new insights and lineage-tracing methods.

Miguel Ganuza, Momoko Yoshimoto

Abstract readReview
In one paragraph

Review in Experimental hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Miguel GanuzaCentre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom. Electronic address: m.ganuza@qmul.ac.uk.
Momoko YoshimotoCenter for Immunology, Department of Investigative Medicine, Western Michigan University Homer Stryker MD School of Medicine, Upjohn Campus, Kalamazoo, Michigan. Electronic address: momoko.yoshimoto@wmed.edu.

Funding

The developmental pathway of fetal-derived B cellsR01AI165798 · NIAID · WESTERN MICHIGAN UNIV SCHOOL OF MEDICINE · PI Nichol Elizabeth Holodick, Momoko Yoshimoto · 2023 to 2026
$2.4M
The Role of Biological Sex in the Self-renewal of B1 Cells into Old Age in Mice and HumansR01AG084752 · NIA · WESTERN MICHIGAN UNIV SCHOOL OF MEDICINE · PI Nichol Elizabeth Holodick, THOMAS L ROTHSTEIN · 2024 to 2026
$2.3M
Different roles of fetal- and adult-derived IgA secreting cells against GI infectionR21AI178153 · NIAID · WESTERN MICHIGAN UNIV SCHOOL OF MEDICINE · PI YOSHIMOTO, MOMOKO · 2023 to 2024
$432k
NIAID NIH HHS R01 AI165798NIAID NIH HHS R21 AI178153NIA NIH HHS R01 AG084752
6 · The paper itself

Abstract

Recent advances in developmental hematology have revealed unappreciated hematopoietic waves and origins during development, and unexpected hematopoietic stem cell (HSC)-independent progenitors that provide lifelong hematopoiesis, using in vivo barcoding technologies and various lineage-tracing mouse models. Also, these tools estimate HSC numbers and display HSC behaviors that have not been anticipated. This review introduces such new discoveries in blood development and discusses the data and controversies.

Indexed as

Cell LineageHematopoiesisHematopoietic Stem CellsAnimalsHumansMice

Identifiers

PMID41397565
PMCPMC12944141

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.