Trial reportBMC gastroenterology2025
Effect of anesthetic nasal mask on hypoxemia in elderly patients undergoing gastroscopy with deep sedation: a randomized controlled trial.
Trial report in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and safety of nasal mask compared to nasal cannula during procedural sedation in gastroscopy: a systematic review, meta-analysis, and trial sequential analysis.BMC anesthesiology · 2026Pooled it
- Efficacy and safety of remimazolam besylate plus propofol for sedation in endoscopic retrograde cholangiopancreatography: a randomized controlled study.Frontiers in medicine · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundThe risk of hypoxemia is increased in elderly patients who are sedated during gastroscopy. This can be attributed to the physiological changes associated with aging, such as reduced oxygen reserves and an increased sensitivity to sedatives. This study aimed to evaluate whether an anesthetic nasal mask is more effective than a traditional nasal cannula at preventing hypoxemia during gastroscopy in elderly patients.
methods300 participants were randomly allocated into traditional nasal cannula group or anesthetic nasal mask group (150 patients in each group). Deep sedation was achieved with intravenous propofol, titrated to maintain spontaneous breathing. The primary outcome was the incidence of hypoxemia (defined as SpO₂ ≤ 92%). Secondary outcomes included the incidence of severe hypoxemia (defined as an intraoperative SpO₂ of ≤ 75% at any time or a hypoxemia duration of ≥ 60 s), duration of hypoxemia, minimum intraoperative SpO₂, incidence of emergency airway interventions, incidence of gastroscopy interruption, procedure duration, recovery time, total propofol dose, satisfaction scores from endoscopists, anesthesiologists and patients, and other adverse events.
resultsCompared with traditional nasal cannulas, using an anaesthetic nasal mask could significantly reduce the incidence of hypoxemia (45.0% vs. 15.5%, p < 0.001). It also increased the minimum intraoperative SpO₂ (from 94.0% to 99.0%; P < 0.001) and reduced the need for jaw thrust (from 37.6% to 13.5%; P < 0.001). Satisfaction levels among endoscopists and anesthesiologists were significantly greater in the anesthetic nasal mask group (P < 0.01). However, there were no significant differences between the two groups in terms of the incidence of severe hypoxemia.
conclusionsElderly patients undergoing gastroscopy with deep sedation experienced a significant reduction in the incidence of hypoxemia when anesthetic nasal masks were used.
trial registrationThe trial was registered with the Chinese Clinical Trial Registry ( https://www.chictr.org.cn , ChiCTR2100053388, registered on 20/11/2021).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.