Evidence map›Paper›PMID 41398613›Full record

ReviewCurrent cardiology reviews2025

Heart Failure Management in the Modern Era: A Comprehensive Review on Medical and Device-based Interventions.

Aman Shrivastava, Niharika Gokhale, Pritesh Paliwal, Sumeet Dwivedi, Shamim Khan, Preetam L Nikam, Yash Jain, Jaya Kumari

Abstract readReview
In one paragraph

Review in Current cardiology reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aman ShrivastavaDepartment of Pharmacology, College of Pharmacy, Institute of Professional Studies, Gwalior, Madhya Pradesh, India.ORCID 0000-0003-0085-4965
Niharika GokhaleFaculty of Pharmacy, Medi-Caps University, Indore, Madhya Pradesh, India.ORCID 0009-0005-9323-7297
Pritesh PaliwalDepartment of Pharmacy, Indore Institute of Pharmacy, Indore, Madhya Pradesh, India.ORCID 0009-0007-6914-2110
Sumeet DwivediDepartment of Pharmacy, Acropolis Institute of Pharmaceutical Education and Research, Indore, Madhya Pradesh, India.ORCID 0000-0003-3592-4812
Shamim KhanIIMT College of Medical Sciences, IIMT University, Ganga Nagar, Meerut, Uttar Pradesh, India.ORCID 0009-0005-6103-1243
Preetam L NikamDepartment of Pharmacy, SND College of Pharmacy, Nashik, Maharashtra, India.ORCID 0000-0002-6604-4060
Yash JainDepartment of Pharmacy Practice, NIMS Institute of Pharmacy, NIMS University, Jaipur, Rajasthan, India.ORCID 0009-0006-1376-9232
Jaya KumariDepartment of Pharmacy Practice, NIMS Institute of Pharmacy, NIMS University, Jaipur, Rajasthan, India.ORCID 0009-0009-5382-6889

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure remains a significant global health challenge, necessitating continuous advancements in management strategies to improve patient outcomes. This review aimed to elucidate the current scenario of heart failure and its management in the modern era, focusing on integrating medical therapy and implantable device interventions. According to guidelines, medical treatment remains the primary method of treating heart failure. Such medications include ACE inhibitors, neprilysin-angiotensin receptor inhibitors, beta-blockers, angiotensin II receptor blockers, mineralocorticoid receptor antagonists, and blockers of sodium-glucose co-transporter- 2. These pharmacologic agents have demonstrated efficacy in decreasing mortality and morbidity in patients. The advent of implantable devices has revolutionized treatment, providing substantial benefits in specific patient populations. Cardiac resynchronization therapy has emerged as a pivotal intervention for patients with reduced ejection fraction and dyssynchronous ventricular contraction, effectively enhancing cardiac function and quality of life. Furthermore, left bundle branch area pacing improvements provide fascinating alternatives to traditional cardiac resynchronization therapy. The essential significance of device-based therapies is further highlighted by the function of implanted cardioverter-defibrillators in preventing unexpected cardiac deaths in high-risk patients. Furthermore, integrating remote monitoring technologies and novel device innovations continues to enhance the precision and efficacy of heart failure management. This review comprehensively examines current guidelines and evidence supporting the use of these therapies, addressing their synergistic potential and the practical considerations for their implementation, while synthesizing recent advancements in pharmacologic and device-based interventions.

Indexed as

Cardiac Resynchronization TherapyDefibrillators, ImplantableDisease ManagementHeart FailureAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsHumansQuality of LifeAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor Antagonistscardiovascular disordersetiology.Heart failureimplantable devicesmedical therapysynergetic potential

Identifiers

PMID41398613
PMCPMC12676028

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.