Evidence map›Paper›PMID 41398626›Full record

Observational studyRenal failure2025

Hemoadsorption therapy in severe rhabdomyolysis: a report from the international, prospective COSMOS (CytOSorb

Ricard Ferrer, Bartosz Tyczynski, Julian Kreutz, Christina Scharf, Matthias Thielmann, Martin Bellgardt, Andreas Kribben, Philipp Hohlstein, Nuno Germano, Dietrich Henzler and 9 more

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ricard FerrerIntensive Care Department, Vall d'Hebron University Hospital, Shock, Organ Dysfunction and Resuscitation Research Group (SODIR), Barcelona, Spain.
Bartosz TyczynskiDepartment of Medical Intensive Care, University Hospital Essen, Essen, Germany.
Julian KreutzDepartment of Cardiology, Angiology, and Intensive Care Medicine, Philipps University of Marburg, University Hospital, Marburg, Germany.
Christina ScharfDepartment of Anesthesiology, LMU university hospital, LMU Munich, Munich, Germany.
Matthias ThielmannDepartment of Thoracic and Cardiovascular Surgery, West German Heart & Vascular Center Essen, University Hospital Duisburg-Essen, Essen, Germany.
Martin BellgardtDepartment of Anesthesiology and Intensive Care Medicine, St Josef-Hospital Bochum, Bochum, Germany.
Andreas KribbenDepartment of Nephrology, University Duisburg-Essen, University-Hospital Essen, Essen, Germany.
Philipp HohlsteinDepartment for Gastroenterology, Metabolic Disorders and Intensive Care Medicine (Department of Medicine III), RWTH-University Hospital Aachen, Aachen, Germany.
Nuno GermanoEmergency Department, Hospital Curry Cabral, Lisboa, Portugal.
Dietrich HenzlerDepartment of Anesthesiology, Surgical Intensive care, Emergency and Pain Medicine, Ruhr-University Bochum, Hospital Herford, Herford, Germany.
Andreas BaumannDepartment of Anesthesiology, Intensive Care Medicine and Pain Management, BG University Hospital Bergmannsheil, Medical Faculty of Ruhr University Bochum, Bochum, Germany.
Moritz UnglaubeDepartment of Intensive Care Medicine, Helios Dr. Horst- Schmidt Klinik Wiesbaden, Wiesbaden, Germany.
Ulf GuentherHospital Oldenburg AöR, University Hospital of Anesthesiology and Intensive Care, Oldenburg, Germany.
Weihong FanMedical Affairs, CytoSorbents Corporation and CytoSorbents Medical Inc, Princeton, New Jersey, USA.
Teresa KlausMedical Affairs, CytoSorbents Europe GmbH, Berlin, Germany.
Volker HumbertMedical Affairs, CytoSorbents Europe GmbH, Berlin, Germany.
Joerg ScheierMedical Affairs, CytoSorbents Europe GmbH, Berlin, Germany.
Efthymios N DeliargyrisMedical Affairs, CytoSorbents Corporation and CytoSorbents Medical Inc, Princeton, New Jersey, USA.
Fabio Silvio TacconeDepartment of Intensive Care, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe rhabdomyolysis is associated with an increased risk of acute kidney injury (AKI) and mortality. Hemoadsorption may reduce myoglobin levels and mitigate AKI. The COSMOS registry is a prospective, multicenter, observational study evaluating hemoadsorption with CytoSorb

Indexed as

Acute Kidney InjuryHemoperfusionRhabdomyolysisAdultAgedCreatinineCritical IllnessFemaleHumansMaleMiddle AgedMyoglobinProspective StudiesRegistriesRenal Replacement TherapyTreatment OutcomeCreatinineMyoglobinAKIblood purificationCytoSorbhemoadsorptionregistryrhabdomyolysis

Identifiers

PMID41398626
PMCPMC12710254

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.