Evidence map›Paper›PMID 41398659›Full record

ArticleBMC pediatrics2025

Rare disease mimicking multisystem inflammatory syndrome in children.

Asuman Akar

Abstract readCase Reports
In one paragraph

Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Asuman AkarFaculty of Medicine DIYARBAKIR, Pediatric Infectious Disease, Dicle University, DIYARBAKIR, Diyarbakir, Turkey. asuman.akar@dicle.edu.tr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multisystem inflammatory syndrome (MIS-C) is a rare but serious condition associated with SARS-CoV-2, the virus that causes COVID-19. We report a 16-year-old female who presented with seven days of fever, abdominal pain, headache, and fatigue. Physical examination revealed meningeal irritation. Laboratory findings showed pancytopenia, elevated inflammatory markers, and positive SARS-CoV-2 IgG with negative PCR. The patient had no history of COVID-19 vaccination or previous confirmed infection. Initially evaluated as MIS-C due to fever, multisystem involvement, and antibody positivity, she was subsequently diagnosed with visceral leishmaniasis after bone marrow aspiration revealed Leishmania amastigotes. This case highlights the diagnostic overlap between MIS-C and endemic infections such as leishmaniasis and underlines the importance of considering infectious etiologies in hyperinflammatory presentations, especially in endemic areas.

Indexed as

COVID-19Leishmaniasis, VisceralRare DiseasesSystemic Inflammatory Response SyndromeAdolescentDiagnosis, DifferentialFemaleHumansSARS-CoV-2Differential diagnosisImmune dysregulationMultisystem inflammatory syndromeSARS-CoV-2Visceral leishmaniasis

Identifiers

PMID41398659
PMCPMC12829272

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.