Evidence map›Paper›PMID 41398770›Full record

ArticleMedicine2025

Composite lipid-inflammatory indices and mortality risk in NHANES 2007-2016.

Xinyue Zhao, Nan Zhang, Tao Yan, Ziying Zhang, Lehui Li, Ning Cao, Jiwen Yang, Xingguang Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinyue ZhaoDepartment of Health Statistics, School of Public Health, Inner Mongolia Medical University, Hohhot, China.ORCID 0009-0006-6398-0095
Nan ZhangDepartment of Environmental and Occupational Health, School of Public Health, Inner Mongolia Medical University, Hohhot, China.
Tao YanDepartment of Health Statistics, School of Public Health, Inner Mongolia Medical University, Hohhot, China.
Ziying ZhangDepartment of Pharmacology, College of Basic Medical Sciences, Inner Mongolia Medical University, Hohhot, China.
Lehui LiDepartment of Environmental Health, School of Public Health, Inner Mongolia Medical University, Hohhot, China.
Ning CaoDepartment of Epidemiology, School of Public Health, Inner Mongolia Medical University, Hohhot, China.
Jiwen YangNeurosurgery Department, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Xingguang ZhangDepartment of Health Statistics, School of Public Health, Inner Mongolia Medical University, Hohhot, China.

Funding

Inner Mongolia Natural Science Foundation 2023QN08030Inner Mongolia Natural Science Foundation 2024MS08016National Natural Science Foundation of China;Inner Mongolia Natural Science Foundation 82160639, 82460666;2024MS08074
6 · The paper itself

Abstract

This study aims to investigate the associations of atherogenic index of plasma (AIP), systemic immune-inflammatory index (SII), monocyte-to-high-density lipoprotein cholesterol ratio (MHR), and neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) with cardiovascular disease (CVD) mortality and all-cause mortality. Utilizing data from the National Health and Nutrition Examination Survey 2007-2016, Cox proportional hazards models were employed to evaluate the relationships between these biomarkers and mortality outcomes. Analysis of 11,188 participants based on Framingham Risk Scores revealed that higher AIP, SII, NHR, and MHR levels are significant risk factors for cardiovascular and all-cause mortality. These associations remained robust after adjusting for covariates including age, sex, race, smoking, and alcohol consumption. Similar trends were observed for all-cause mortality. AIP, SII, MHR, and NHR are associated with an increased risk of CVD and all-cause mortality, suggesting their potential utility as novel biomarkers for risk stratification in clinical practice.

Indexed as

Cardiovascular DiseasesInflammationAdultAgedBiomarkersCholesterol, HDLFemaleHumansMaleMiddle AgedNeutrophilsNutrition SurveysProportional Hazards ModelsRisk AssessmentRisk FactorsUnited StatesBiomarkersCholesterol, HDLatherogenic index of plasmacardiovascular diseasemonocyte-to-high-density lipoprotein cholesterol rationeutrophil-to-high-density lipoprotein cholesterol ratiosystemic immune-inflammatory index

Identifiers

PMID41398770
PMCPMC12708090

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.