Evidence map›Paper›PMID 41399358›Full record

ArticleMaterials today. Bio2025

Bifunctional 3D-printed PEEK scaffolds incorporating hydrogel-encapsulated magnesium-quinone nanosheets for antibacterial activity and mandibular bone regeneration.

Qiao Su, Tianying Luo, Meng Pan, Jun Liu, Hui Yang, Xulin Hu, Zhiyong Qian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. ["Chongqing experiences" in treatment of bone infections].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiao SuState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Tianying LuoDepartment of Biotherapy, Cancer Center, and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
Meng PanDepartment of Biotherapy, Cancer Center, and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jun LiuState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Hui YangState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.
Xulin HuDepartment of Biotherapy, Cancer Center, and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
Zhiyong QianDepartment of Biotherapy, Cancer Center, and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious mandibular bone defects present significant clinical challenges due to the complex pathological microenvironment, risk of persistent bacterial colonization, and insufficient bone regeneration. Poly (ether ketone) (PEEK) is considered a promising alternative to metallic implants owing to its bone-mimetic mechanical properties; however, its intrinsic hydrophobicity and bioinertness hinder osseointegration and functional recovery. Here, a bifunctional 3D-printed porous PEEK scaffold coated with an alginate hydrogel encapsulating magnesium-aloe emodin (MgAe) nanosheets (AP@MgAe) was developed to achieve simultaneous antibacterial and osteogenic functions. MgAe nanosheets were synthesized via metal-quinone coordination-driven self-assembly, enabling the co-delivery of bioactive Mg

Indexed as

3D-printed PEEK scaffoldAntibacterial activityInfectious mandibular bone defectsMagnesium-quinone nanosheetsOsteogenesis therapy

Identifiers

PMID41399358
PMCPMC12702351

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.