ArticleJTCVS structural and endovascular2025
Characterizing growth and early hemodynamic inefficiencies: Phase-contrast magnetic resonance imaging analysis of the aorta in post-Fontan hypoplastic left heart syndrome.
Article in JTCVS structural and endovascular, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To address the lack of routine hemodynamic assessment during aortic reconstruction in patients with hypoplastic left heart syndrome (HLHS) with a momentum-based metric from phase-contrast magnetic resonance imaging (MRI) data (4D Flow). Methods: 4D Flow data were acquired in 100 subjects, including 22 Post-Fontan HLHS subjects (15 children, mean age 8.0 ± 1.7 years and 7 adolescents, mean age 15.1 ± 1.9 years) and 78 control subjects (mean age 7.6 ± 1.0 years). Comparative anatomic and functional analyses were performed in 4 segments: ascending aorta (AA), transverse arch (TA), and proximal and distal descending aortas (DA1 and DA2). Aortic growth was evaluated by its diameter indexed by body surface area, and early energy inefficiency was assessed by the advective pressure drop (PD Results: Post-Fontan HLHS children presented with early hemodynamic inefficiency at the TA-DA1 transition (median PD Conclusions: Early hemodynamic inefficiencies in the TA-DA1 transition in the HLHS aorta have been characterized. The PD
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