Evidence map›Paper›PMID 41399408›Full record

ReviewJournal of pharmaceutical analysis2025

Mitochondrial membrane chromatography: Discovery of mitochondrial targeting modulators.

Wu Su, Yu Kong, Hua Li, Yongyao Wang, Lizhuo Wang, Le Shi, Huaizhen He, Shengli Han, Hui Guo, Jiankang Liu and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of pharmaceutical analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wu SuSchool of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710116, China.
Yu KongSchool of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710116, China.
Hua LiSchool of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710116, China.
Yongyao WangSchool of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710116, China.
Lizhuo WangSchool of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710116, China.
Le ShiSchool of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710116, China.
Huaizhen HeSchool of Pharmacy, Xi'an Jiaotong University, Xi'an, 710061, China.
Shengli HanSchool of Pharmacy, Xi'an Jiaotong University, Xi'an, 710061, China.
Hui GuoDepartment of Endocrinology, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, 710000, China.
Jiankang LiuSchool of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710116, China.
Jiangang LongSchool of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710116, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria are fundamental organelles that play a crucial role in cellular energy metabolism, substance metabolism, and various essential cellular signaling pathways. The dysfunction of mitochondria is significantly implicated in the onset and progression of aging, neurodegenerative diseases, metabolic disorders, and tumors, thereby rendering mitochondria-targeted regulation, a vital strategy for disease prevention and treatment. The recently developed mitochondrial membrane chromatography (MMC) technique, which immobilizes mitochondrial proteins as a chromatographic separation medium, has shown great potential for efficiently screening mitochondria-targeted modulators from complex compound library. In contrast to traditional screening methods, MMC has no need to purify mitochondrial proteins and can preserve its

Indexed as

Major chronic diseasesMitochondrial membrane chromatographyMitochondrial modulatorsMitochondrial nutrientsMolecular screening

Identifiers

PMID41399408
PMCPMC12702217

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.