Evidence map›Paper›PMID 41399999›Full record

SynthesisLa Medicina del lavoro2025

Effectiveness of Occupational Health Promotion Programs on Cardiometabolic risk factors: A Systematic Review and Three-Level Meta-Analysis.

Alessandro Godono, Veruscka Leso, Ettore Paradisi, Elisa Carena, Maria Vittoria Picciaiola, Anna Schneider-Kamp, Catalina Ciocan, Fabrizio Bert, Franco Veglio, Paolo Boffetta and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in La Medicina del lavoro, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alessandro GodonoDepartment of Public Health and Paediatric Sciences, University of Turin, Turin, Italy.ORCID 0000-0001-8095-5461
Veruscka LesoDepartment of Public Health, Section of Occupational Medicine, University of Naples Federico II, Naples, Italy.ORCID 0000-0002-3039-2856
Ettore ParadisiDepartment of Public Health and Paediatric Sciences, University of Turin, Turin, Italy.
Elisa CarenaDepartment of Public Health and Paediatric Sciences, University of Turin, Turin, Italy.
Maria Vittoria PicciaiolaDepartment of Public Health and Paediatric Sciences, University of Turin, Turin, Italy.
Anna Schneider-KampDepartment of Business and Management, University of Southern Denmark, Odense, Denmark.ORCID 0000-0001-9822-6996
Catalina CiocanDepartment of Public Health and Paediatric Sciences, University of Turin, Turin, Italy.
Fabrizio BertDepartment of Public Health and Paediatric Sciences, University of Turin, Turin, Italy.ORCID 0000-0002-4329-9028
Franco VeglioInternal Medicine and Hypertension Division, Department of Medical Sciences, University of Turin, Italy.ORCID 0000-0002-6654-6247
Paolo BoffettaDepartment of Family, Population & Preventive Medicine, Stony Brook University, Stony Brook, New York; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.ORCID 0000-0002-3811-2791
Ivo IavicoliDipartimento di Sicurezza e Bioetica, Catholic University of Sacred Heart, Rome, Italy; Fondazione Policlinico Universitario A. Gemelli, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to evaluate the effectiveness of workplace-based health promotion programs targeting cardiometabolic risk factors.

methodsWe conducted a systematic review and three-level random-effects meta-analysis following PRISMA guidelines, covering studies published from January 2019 to September 2024. Eligible studies included randomized controlled trials (RCTs) and quasi-experimental (QE) designs assessing workplace interventions to reduce cardiometabolic risks in adult workers. Twelve outcomes were considered. Subgroup analyses and meta-regressions were performed to explore sources of heterogeneity. Certainty of evidence was evaluated using GRADE assessment tool.

resultsForty-four studies (30 RCTs, 14 QE) involving 49,813 participants were included. Significant improvements were found in nine of twelve outcomes. These included reductions in BMI (-0.61kg/m²; [-0.93; -0.29]), body weight (-2.43kg; [-3.48; -1.38]), waist circumference (-3.46cm; [-5.21; -1.71]), body fat (-1.58%; [-2.40; -0.76]), systolic (-3.75mmHg: [-5.67; -1.82]) and diastolic (mmHg; [-3.58; -1.29]) blood pressure, LDL cholesterol (-5.9 mg/dL; [-11.6; -0.12]), and an increase in HDL cholesterol (2.76 mg/dL; [0.42; 5.09]). All significant outcomes were supported by moderate-to-high certainty evidence except LDL cholesterol, which was rated very low. Non-significant results were observed for total cholesterol, triglycerides and FBG. High heterogeneity was observed. Pre-existing health conditions, author and duration of intervention partially explained between-study heterogeneity.  Conclusions: Workplace health promotion programs were associated with improvements in various cardiometabolic health indicators. Greater effectiveness was observed in interventions targeting high-risk populations, delivered by physicians or qualified health professionals, and implemented over shorter durations. Findings support the integration of such programs into occupational health policies and broader public health strategies. Future research should optimize intervention designs, extend follow-up, and consider integrated approaches to maximize long-term benefits.

Indexed as

Cardiometabolic Risk FactorsCardiovascular DiseasesHealth PromotionOccupational HealthHumansRandomized Controlled Trials as Topic

Identifiers

PMID41399999
PMCPMC12815280

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.