Evidence mapPaperPMID 41400876Full record

ReviewTopics in current chemistry (Cham)2025

Progress in the Synthesis and Application of Phycocyanin-Based Nanoparticles.

Fatemeh Rahmati-Dehkordi, Siavash Abdolghaderi, Felora Ferdosi, Neda Ebrahimi, Abdolkarim Talebi Taheri, Ehsan Dadgostar, Fatemeh Nabavizadeh, Mehdi Shafiee Ardestani, Mozhdeh Mohammadpour, Rajender S Varma and 1 more

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In one paragraph

Review in Topics in current chemistry (Cham), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fatemeh Rahmati-DehkordiStudents' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Siavash AbdolghaderiDepartment of Physical Medicine and Rehabilitation, Iran University of Medical Sciences, Tehran, Iran.
Felora FerdosiDepartment of Radiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Neda EbrahimiDepartment of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Abdolkarim Talebi TaheriStudents' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Ehsan DadgostarBehavioral Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran.
Fatemeh NabavizadehElectrophysiology Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Mehdi Shafiee ArdestaniDepartment of Radio Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Mozhdeh MohammadpourDepartment of Physical Medicine and Rehabilitation, Iran University of Medical Sciences, Tehran, Iran. Mozhde.mohammadpour73@gmail.com.
Rajender S VarmaDepartment of Chemistry, Centre of Excellence for Research in Sustainable Chemistry, Federal University of São Carlos, São Carlos, SP, 13565-905, Brazil. rajvarma@hotmail.com.
Omid Reza TamtajiElectrophysiology Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran. tamtaji.or@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phycocyanin, a phycobiliprotein, is a known antimicrobial and anticancer compound, and among nanoparticle formulations, its use has garnered significant attention regarding the treatment of cancers and bacterial and parasitic diseases. Phycocyanin has been deployed in a wide range of nanoparticles amid polymer (chitosan, polylactic acid-co-glycolic acid, polypyrrole, and hydrogel nanoparticles) and non-polymer (liposomes, phytosomes, micelles, microspheres, manganese dioxide, and black phosphorus quantum dots) entities. Phycocyanin-based nanoparticles were previously limited to utilizing their anticancer and antimicrobial effects, but recent studies have revealed that they target a variety of cellular and molecular processes, such as apoptosis, cell cycle arrest, angiogenesis, and metastasis. In addition, phycocyanin-based nanoparticles have demonstrated efficacy in inhibiting the growth of various parasites and bacteria, including Cryptosporidium, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Serratia marcescens, and Bacillus cereus. Herein, various forms of phycocyanin-based nanoparticles are evaluated, emphasizing the cellular and molecular pathways involved in cancer and microbial therapy.

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsNanoparticlesPhycocyaninAnimalsBacteriaHumansAnti-Bacterial AgentsAntineoplastic AgentsPhycocyaninAnticancerAntimicrobialNanoformulationPhycocyaninTherapeutic applications

Identifiers

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.