Evidence map›Paper›PMID 41400920›Full record

Observational studyEuropean geriatric medicine2026

Medication review in older adults at hospital discharge: an analysis of data from the IATROPREV study.

Chloé Cornille, Jean-Baptiste Beuscart, Bertrand Décaudin, François Puisieux, Roxane Girault, Lisa Mondet, Anne Toulemonde, Sophie Gautier, Grégory Tempremant, Jean-Paul Kornobis and 4 more

Abstract readObservational StudyMulticenter Study
PubMed Publisher
In one paragraph

Observational study in European geriatric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chloé CornilleMP3CV Laboratory, EA7517, CURS, Faculty of Pharmacy, Jules Verne University of Picardie, Amiens University Hospital, 1 Rue du Professeur Christian Cabrol, F-80000, Amiens, France. cornille.chloe@gmail.com.ORCID http://orcid.org/0009-0001-6161-5477
Jean-Baptiste BeuscartDepartment of Geriatric Medicine, Lille University Hospital, Lille, France.
Bertrand DécaudinInstitute of Pharmacy, Lille University Hospital, Lille, France.
François PuisieuxDepartment of Geriatric Medicine, Lille University Hospital, Lille, France.
Roxane GiraultUniversity Lille, CHU Lille, ULR 2694-METRICS: Evaluation des technologies de santé et des pratiques médicales, Lille, France.
Lisa MondetDepartment of Pharmacy, Amiens University Hospital, Amiens, France.
Anne ToulemondeDepartment of Geriatric Medicine, Lille University Hospital, Lille, France.
Sophie GautierDepartment of Pharmacovigilance, Lille University Hospital, Lille, France.
Grégory TempremantURPS Pharmacists Hauts-de-France, Lille, France.
Jean-Paul KornobisURPS Physicians Hauts-de-France, Lille, France.
Mathilde DambrineInstitute of Pharmacy, Lille University Hospital, Lille, France.
Frédéric BlochDepartment of Geriatric Medicine, Amiens University Hospital, Amiens, France.
Aurélie LengletMP3CV Laboratory, EA7517, CURS, Faculty of Pharmacy, Jules Verne University of Picardie, Amiens University Hospital, 1 Rue du Professeur Christian Cabrol, F-80000, Amiens, France.
IATROPREV collaborative group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeReducing drug-related problems is a major challenge in older adults taking multiple medications. The IATROPREV program aims to improve prescribing appropriateness through multidisciplinary medication optimization, a personalized pharmaceutical plan (PPP), and direct, structured communication between hospital and community healthcare professionals. To analyze the medication optimizations generated by IATROPREV and validated by healthcare professionals through inclusion in PPPs. Potentially inappropriate medications (PIMs) were identified using the Anatomical Therapeutic Chemical (ATC) classification and the REview of potentially inappropriate MEDIcation pr(e)scribing in Seniors (REMEDI(e)S) criteria.

methodsIATROPREV was a prospective, observational, multicenter study (2021-2024) conducted in two French university hospitals. It involved 504 patients admitted to geriatric units. Multidisciplinary meetings brought together geriatricians, attending physicians, hospital pharmacists, and community pharmacists. The patients' prescriptions before and after hospitalization were compared, and PIMs were screened using 73 REMEDI[e]S criteria.

resultsA total of 4977 prescriptions were analyzed. 38% of the recommendations involved discontinuations, 20% modifications, and 37% additions. 42% of prescriptions remained unchanged. Most optimizations targeted ATC classes A (alimentary tract and metabolism), C (the cardiovascular system), and N (the nervous system). Additions mainly involved class A drugs (e.g., laxatives, vitamins), while discontinuations frequently affected class C drugs (e.g., renin-angiotensin-aldosterone system inhibitors, lipid-lowering drugs). PIMs decreased from 1437 at inclusion to 936 at discharge (-35%), with variations across REMEDI[e]S criteria.

conclusionIATROPREV highlights the complexity of medication optimizations in geriatrics. Although the REMEDI[e]S criteria enable partial assessment, they do not fully capture all clinically relevant adjustments made through the program.

Indexed as

Inappropriate PrescribingMedication ReconciliationPatient DischargePotentially Inappropriate Medication ListAgedAged, 80 and overFemaleFranceHumansMalePolypharmacyProspective StudiesMedication reviewPolypharmacyPotentially inappropriate medicationsTherapeutics optimization

Identifiers

PMID41400920

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.