ArticleNeuroimmunomodulation2026
Inflammation and Perceived Social Support in Elite Athletes (A Quantile Regression Approach).
Article in Neuroimmunomodulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionInflammation and social relationships are bidirectionally linked, yet evidence in young, nonclinical populations is scarce. Given that elite athletes face continuous immune challenges and unique social conditions, this cohort provides a model to explore this association.
methodsSeveral quantile regressions were computed across 422 elite athletes. To account for both the magnitude of inflammation and the characteristics of social relationships, quantiles were determined based on the concentrations of tumor necrosis factor alpha, interleukin-6, and the systemic inflammatory response index (SIRI) as well as on measures of the total, general perceived social support. The corresponding predictors were social support and the inflammatory markers.
resultsA higher total, general perceived social support predicted a significantly lower SIRI in the lowest quartile as well as lower concentrations of the cytokines in the highest three quartiles. Effects were small but robust. Moreover, higher inflammation predicted a lower total, general perceived social support in elite athletes, when the perceived social support was relatively moderate. However, this effect was not robust when covariates, such as urea or the living situation, were added to the models.
conclusionResults suggest that elite athletes' social relationships are a small yet important factor influencing the inflammatory response. The social support elite athletes perceive, however, appears to be influenced by inflammation only under specific biopsychosocial conditions.
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