Evidence mapPaperPMID 41401426Full record

ReviewFunction (Oxford, England)2026

Molecular mechanisms of acute inflammation: systemic responses and kidney-specific pathophysiology.

Forough Chelangarimiyandoab, Jean-Philippe C Lavoie, Nicolas Flamand, Emmanuelle Cordat, Sylvie Breton

Abstract readReview
In one paragraph

Review in Function (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Forough ChelangarimiyandoabDepartment of Physiology and Membrane Protein Disease Research Group, Faculty of Medicine & Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Jean-Philippe C LavoieFaculty of Medicine, Department of Obstetrics, Gynecology and Reproduction, Centre Hospitalier Universitaire de Québec-Research Centre, and Centre de Recherche en Reproduction, Développement et Santé Intergénérationnelle-Université Laval, Québec City, Québec, Canada.ORCID 0000-0002-8976-647X
Nicolas FlamandFaculty of Medicine, Department of Medicine, Centre de recherche de l'Institut Universitaire de Cardiologie et Pneumologie de Québec, Université Laval, Québec City, Québec, Canada.
Emmanuelle CordatDepartment of Physiology and Membrane Protein Disease Research Group, Faculty of Medicine & Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Sylvie BretonFaculty of Medicine, Department of Obstetrics, Gynecology and Reproduction, Centre Hospitalier Universitaire de Québec-Research Centre, and Centre de Recherche en Reproduction, Développement et Santé Intergénérationnelle-Université Laval, Québec City, Québec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is a critical immune response to tissue injury or infection, involving a cascade of molecular and cellular events. This review examines acute inflammation, focusing on the key receptors, signaling pathways, mediators, and cellular players involved in the response throughout the body. The latter part of the review narrows its focus to kidney inflammation, a vital organ often affected by both sterile and nonsterile insults. By exploring the roles of immune and nonimmune cells, this review highlights general inflammatory mechanisms and their impact on kidney-specific pathophysiology.

Indexed as

InflammationKidneyAcute DiseaseAnimalsHumansSignal Transductioninfectious inflammationinnate immunitylipid mediators of inflammationsterile inflammation

Identifiers

PMID41401426
PMCPMC12790851

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.