Evidence map›Paper›PMID 41401648›Full record

ArticleUltrasonics sonochemistry2026

Preparation and characterization of ultrasound-mediated Ocimum basilicum L. essential oil nanoemulsion and its application in meat preservation.

Yue Wang, Weixuan Pan, Xiangjun Yang, Ende Song, Hui Zhang, Yiming Liu, Kehui Wang, Huiwen Wu, Qi Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasonics sonochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yue WangThe First School of Clinical Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, PR China; Key Laboratory of the Jiangsu Higher Education Institutions for Integrated Traditional Chinese and Western Medicine in Senile Diseases Control (Yangzhou University), Yangzhou 225009, PR China.
Weixuan PanSchool of Traditional Chinese Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, PR China; Key Laboratory of the Jiangsu Higher Education Institutions for Integrated Traditional Chinese and Western Medicine in Senile Diseases Control (Yangzhou University), Yangzhou 225009, PR China.
Xiangjun YangThe First School of Clinical Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, PR China; Key Laboratory of the Jiangsu Higher Education Institutions for Integrated Traditional Chinese and Western Medicine in Senile Diseases Control (Yangzhou University), Yangzhou 225009, PR China.
Ende SongThe First School of Clinical Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, PR China; Key Laboratory of the Jiangsu Higher Education Institutions for Integrated Traditional Chinese and Western Medicine in Senile Diseases Control (Yangzhou University), Yangzhou 225009, PR China.
Hui ZhangThe First School of Clinical Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, PR China; Key Laboratory of the Jiangsu Higher Education Institutions for Integrated Traditional Chinese and Western Medicine in Senile Diseases Control (Yangzhou University), Yangzhou 225009, PR China.
Yiming LiuSchool of Traditional Chinese Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, PR China; Key Laboratory of the Jiangsu Higher Education Institutions for Integrated Traditional Chinese and Western Medicine in Senile Diseases Control (Yangzhou University), Yangzhou 225009, PR China.
Kehui WangSchool of Traditional Chinese Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, PR China; Key Laboratory of the Jiangsu Higher Education Institutions for Integrated Traditional Chinese and Western Medicine in Senile Diseases Control (Yangzhou University), Yangzhou 225009, PR China.
Huiwen WuScience and Technology Center of Fenyang College, Shanxi Medical University, Fenyang 032200, PR China; Cultivation Key Laboratory of Metabolic Cardiovascular Diseases Research, Fenyang 032200, PR China; Department of Oncology, Shanxi Province Fenyang Hospital, Fenyang 032200, PR China. Electronic address: huiwenwu@sxmu.edu.cn.
Qi LiuSchool of Traditional Chinese Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, PR China; Key Laboratory of the Jiangsu Higher Education Institutions for Integrated Traditional Chinese and Western Medicine in Senile Diseases Control (Yangzhou University), Yangzhou 225009, PR China. Electronic address: liuqi@yzu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a stable basil oil nanoemulsion was prepared by emulsifier-assisted ultrasonication. The optimized formulation exhibited excellent physical stability under ambient, refrigerated (4 °C), and heated (55 °C) conditions. It demonstrated strong antibacterial activity against E. coli and S. aureus, inducing membrane disruption and oxidative stress, as evidenced by elevated ROS and MDA levels. The nanoemulsion also showed significant antioxidant capacity, scavenging 95 % of DPPH and 86 % of ABTS radicals and achieving a FRAP value of 14.6 µmol/g at 200 µg/mL. Cytotoxicity analysis confirmed high biocompatibility, with cell viability exceeding 83 % in L02 and BEAS-2B cells at 16 mg/mL. When applied to beef packaging, the nanoemulsion effectively maintained pH, reduced microbial counts, and suppressed TVB-N accumulation, thereby prolonging meat freshness. These findings highlight its potential as a multifunctional preservative for food and biomedical applications.

Indexed as

Food PreservationMeatNanostructuresOcimum basilicumOils, VolatileSonicationUltrasonic WavesAnimalsAnti-Bacterial AgentsAntioxidantsCell LineCell SurvivalEmulsionsEscherichia coliHumansStaphylococcus aureusAnti-Bacterial AgentsAntioxidantsEmulsionsOils, VolatileApplication in meat preservationBasil essential oilNanoemulsionUltrasound

Identifiers

PMID41401648
PMCPMC12769834

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.