ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2025
[Association between insulin resistance and idiopathic central precocious puberty in girls and the diagnostic value of insulin resistance].
Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo explore the relationship between insulin resistance and idiopathic central precocious puberty (ICPP) in girls and the diagnostic value of insulin resistance.
methodsClinical data of 245 girls aged 4 to 7.5 years with low luteinizing hormone (LH) levels (0.2-0.83 IU/L), normal body weight (body mass index standard deviation score between -2 and +2), and early breast development who visited the Department of Pediatric Endocrinology, Henan Provincial Maternal and Child Health Hospital from January 2022 to March 2025 were retrospectively analyzed. According to the Expert Consensus on the Diagnosis and Treatment of Central Precocious Puberty (2022), patients were assigned to an ICPP group (
resultsHOMA-IR was higher in the ICPP group than in the control group (
conclusionsHOMA-IR is closely associated with ICPP in girls with low LH and normal body weight, and combining HOMA-IR with basal LH improves early identification and diagnostic efficiency in this population.
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