ReviewJournal of evidence-based medicine2025
Umbrella Reviews: Concepts, Methodological Frameworks, and Step-by-Step Implementation.
Review in Journal of evidence-based medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Exercise-induced changes in systemic inflammatory biomarkers in overweight and obese populations: a bibliometric analysis and umbrella review of meta-analyses.Frontiers in immunology · 2026Pooled it
- Stem cell and extracellular vesicle therapies for wound healing: An umbrella review of predominantly diabetic and preclinical evidence.Cell transplantationPooled it
- Recalibrating evidence hierarchies in populous low- and middle-income countries: Opportunity cost, epistemic alignment, and the overproduction of systematic reviews.Journal of family medicine and primary care · 2026Review
- Virtual Reality in Chronic Conditions: An Umbrella Review.Nursing reports (Pavia, Italy) · 2026Review
- Network Meta-Analysis and Umbrella Review: Complementary, Not Competing, Tools of Evidence Synthesis.Cureus · 2026Article
- Umbrella Reviews: Concepts, Methodological Frameworks, and Step-by-Step Implementation.Journal of evidence-based medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The exponential growth of secondary literature has created an imperative for researchers to identify credible and methodologically sound studies within an increasingly complex information landscape. In light of the growing emphasis on evidence-based medicine in both domestic and international contexts, umbrella reviews (URs) have emerged as a critical methodological approach in biomedical research. As an advanced form of tertiary evidence synthesis, URs systematically integrate findings from multiple systematic reviews and meta-analyses, thereby providing a comprehensive evidence base for specific research questions or related fields. This methodological framework enhances the quality of evidence through critically evaluating the validity and reliability of conclusions drawn from secondary or primary studies. The present overview systematically examines the conceptual framework, distinctive characteristics, development process, and methodological quality assessment of URs, with the objective of establishing a theoretical foundation and practical reference for future research in this domain.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.