Evidence map›Paper›PMID 41403591›Full record

ArticleArchives of medical science : AMS2025

Implications for the role of natural products in Parkinson disease therapy.

Ashwaq H Batawi

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ashwaq H BatawiDepartment of Biological Science, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans still suffer from several nervous system diseases affecting perception and body movement, such as Alzheimer's and Parkinson's diseases. Parkinson's disease is a globally common disease of the nervous system that is characterized by neurodegenerative movement disorders. Patients with Parkinson's disease are characterized by the slow loss of dopaminergic (DA-ergic) neurons, especially in areas of brain tissue called the substantia nigra pars compacta. However, there is still no clear evidence regarding the factors responsible for development of the disease, which remains vague. There are some indications that oxidative stress and mitochondrial dysfunction are among the main causes of the disease. Parkinson's patients are still dependent on taking levodopa as the recommended therapeutic drug. This drug, although it has many side effects, slows down the progression of the disease. Therefore, many scientists and pharmacologists are striving to find a potential drug that can halt the disease while minimizing side effects. Research is underway to find effective natural substances against Parkinson's disease that can renew the vitality of mitochondria and activate their function, as well as diminish the oxidation process in the nerve cells. Therefore, the aim of this review was to highlight the potential role of some natural products from plant sources, such as natural medicinal herbs or marine sources, in protecting neurons and improving their biological functions in order to develop new therapeutic strategies against Parkinson's disease.

Indexed as

genetic and environmental factorsgenetic variantsmedicinal plantsmitochondriaoxidative stressParkinson’s disease

Identifiers

PMID41403591
PMCPMC12703608

What Socratic holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.