Evidence map›Paper›PMID 41404187›Full record

ReviewJournal of extracellular biology2025

Expanding Horizons: Next-Generation and Interdisciplinary Advances in the Applications of Extracellular Vesicles.

Esperanza González, Juan Manuel Falcón-Pérez

Abstract readReview
In one paragraph

Review in Journal of extracellular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Esperanza GonzálezExosomes Laboratory, Center for Cooperative Research in Biosciences (CIC bioGUNE) Basque Research and Technology Alliance (BRTA) Derio Spain.ORCID https://orcid.org/0000-0002-3831-4596
Juan Manuel Falcón-PérezExosomes Laboratory, Center for Cooperative Research in Biosciences (CIC bioGUNE) Basque Research and Technology Alliance (BRTA) Derio Spain.ORCID https://orcid.org/0000-0003-3133-0670

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are increasingly recognized as universal mediators of communication in nature across all domains of life and as versatile tools with roles spanning a wide range of industries. Although EVs have been extensively studied in biomedicine, mainly in diagnostic and nanotherapy of cancer and neurodegenerative diseases, their potential applications in other impactful society areas are only beginning to be explored. Microbial EVs contribute significantly to biofilm formation, virulence and the transmission of antibiotic resistance, highlighting their importance in pathogenicity and infection control. In the aesthetic and dermatological sectors, EVs are gaining traction as innovative agents for skin regeneration, anti-ageing and inflammation modulation, with applications extending to cosmetic dermatology and non-invasive treatments. Veterinary medicine is also exploring EVs for diagnostics and therapeutic delivery, while in agriculture, they show promise in improving crop resilience, acting as natural biopesticides and supporting plant-microbe interactions. Inter-species and interkingdom EV communication understanding, potentially help pest control and disease prevention. Moreover, EVs are being investigated as biosensors for environmental pollution and as agents in soil and water remediation. In the food industry, EVs are explored for their functional benefits in promoting gut and systemic health. However, to fully realize their potential, challenges in large-scale production, quality control and regulatory approval must be addressed. In this article, innovative solutions and potential of EVs across other health issues, environment, agriculture and biotechnology have been revised and discussed.

Indexed as

bioremediationbusiness opportunitycosmeticsdermatologyecologyextracellular vesiclesfunctional foodinterkingdom

Identifiers

PMID41404187
PMCPMC12703056

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.