Evidence map›Paper›PMID 41404368›Full record

ArticleFrontiers in cellular and infection microbiology2025

Prevalence of six respiratory pathogens among children in Chengdu, China: a multiplex PCR-based detection study.

Chenggui Liu, Jiuda Li, Yao Deng, Qin Wang, Xuemei Wang, Shuzhe Yang, Weijun He, Zhiyong Liao

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chenggui Liu *Department of Performance Appraisal Management, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Jiuda Li *Department of Performance Appraisal Management, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Yao DengDepartment of Clinical Laboratory, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Qin WangDepartment of Clinical Laboratory, Sichuan Province Orthopedic Hospital, Chengdu, China.
Xuemei WangDepartment of Clinical Laboratory, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Shuzhe YangDepartment of Clinical Laboratory, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Weijun HeDepartment of Clinical Laboratory, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Zhiyong LiaoDepartment of Clinical Laboratory, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Respiratory tract infections among children are commonly caused by several pathogens, and their prevalence varies across different groups. The goal of this study is to investigate the prevalence of Influenza A virus (Flu A), Influenza B virus (Flu B), respiratory syncytial virus (RSV), Adenovirus (ADV), Rhinovirus (RV), and Methods: This retrospective cross-sectional study included 39,190 children, with 21,847 males and 17,343 females. All respiratory specimens from the participants were tested for Flu A, Flu B, RSV, ADV, RV, and MP using multiplex PCR. Results: The overall prevalence of single infection, double co-infection, and triple co-infection was 48.19%, 7.09%, and 0.25%, respectively. The pathogen-specific prevalence from highest to lowest was RV (21.43%), ADV (16.69%), MP (11.73%), RSV (8.12%), Flu A (3.78%), and Flu B (1.37%). Significant differences were observed in the prevalence of the six pathogens across all six age groups (all Conclusions: Over half of the children were infected with at least one of the six respiratory pathogens, with RV, ADV, and MP being predominant. While co-infections were less common than single infections, they still occurred, with double co-infections being the main form. Notably, the prevalence varied significantly by age, season, and clinical diagnosis. These findings may offer useful references for developing targeted prevention and control strategies.

Indexed as

CoinfectionRespiratory Tract InfectionsAdenoviridaeAdolescentAge FactorsChildChild, PreschoolChinaCross-Sectional StudiesFemaleHumansInfantInfant, NewbornInfluenza A virusInfluenza B virusMaleadenoviruschildreninfluenza A virusinfluenza B virusMycoplasma pneumoniaerespiratory syncytial virusrespiratory tract infectionsrhinovirus

Identifiers

PMID41404368
PMCPMC12702978

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.