Evidence map›Paper›PMID 41405126›Full record

ArticleACS infectious diseases2026

Discovery of Ionophoroantibiotics as a New Antibiotic Class Targeting Metal Homeostasis in Multidrug-Resistant

Freda E-C Jen, Ibrahim M El-Deeb, Jennifer L Edwards, Andrea Maggioni, Michael P Jennings, Mark von Itzstein

Abstract read
In one paragraph

Article in ACS infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Freda E-C JenInstitute for Biomedicine and Glycomics, Griffith University, Gold Coast Campus, Southport Queensland 4222, Australia.ORCID 0000-0003-0475-7396
Ibrahim M El-DeebInstitute for Biomedicine and Glycomics, Griffith University, Gold Coast Campus, Southport Queensland 4222, Australia.
Jennifer L EdwardsThe Center for Microbe and Immunity Research, The Abigail Wexner Research Institute at Nationwide Children's Hospital and The Department of Pediatrics, The Ohio State University, Columbus, Ohio 43210, United States.
Andrea MaggioniInstitute for Biomedicine and Glycomics, Griffith University, Gold Coast Campus, Southport Queensland 4222, Australia.ORCID 0000-0002-6273-5374
Michael P JenningsInstitute for Biomedicine and Glycomics, Griffith University, Gold Coast Campus, Southport Queensland 4222, Australia.ORCID 0000-0002-1027-4684
Mark von ItzsteinInstitute for Biomedicine and Glycomics, Griffith University, Gold Coast Campus, Southport Queensland 4222, Australia.ORCID 0000-0001-6302-7524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rise of multidrug-resistant (MDR)

Indexed as

Anti-Bacterial AgentsDrug Resistance, Multiple, BacterialHomeostasisIonophoresMetalsNeisseria gonorrhoeaeGonorrheaHumansMicrobial Sensitivity TestsZincAnti-Bacterial AgentsIonophoresMetalsZincantibioticsdrug discoveryionophoreNeisseria gonorrhoeae

Identifiers

PMID41405126
PMCPMC12797230

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.