Evidence map›Paper›PMID 41406360›Full record

ReviewSmall (Weinheim an der Bergstrasse, Germany)2026

Transducer Systems Integrated into Organ-on-a-Chip Devices: From Detection to Fabrication.

Gabriel M Ferreira, Patrícia C Sousa, Susana O Catarino, Graça Minas

Abstract readReview
In one paragraph

Review in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gabriel M FerreiraMicroelectromechanical Systems Research unit (CMEMS-UMinho), School of Engineering, Campus de Azurém, University of Minho, Guimarães, 4800-058, Portugal.
Patrícia C SousaInternational Iberian Nanotechnology Laboratory, INL, Braga, 4715-330, Portugal.
Susana O CatarinoMicroelectromechanical Systems Research unit (CMEMS-UMinho), School of Engineering, Campus de Azurém, University of Minho, Guimarães, 4800-058, Portugal.
Graça MinasMicroelectromechanical Systems Research unit (CMEMS-UMinho), School of Engineering, Campus de Azurém, University of Minho, Guimarães, 4800-058, Portugal.ORCID https://orcid.org/0000-0003-2460-0556

Funding

Foundation for Science and Technology, I.P. (FCT, I.P)Fundação para a Ciência e a Tecnologia PTDC/EEI-EEE/2846/2021R&D Unit Project Scope LA/P/0029/2020R&D Unit Project Scope UID/4436/2025Scientific Research and Technological Development Projects (IC&DT)
6 · The paper itself

Abstract

Organ-on-a-chip (OoC) devices are an emerging class of advanced microfluidic systems that replicate human physiological functions at the microscale. Enabled by advances in microfabrication techniques (cleanroom-based microfabrication and 3D printing technologies) and tissue engineering, OoCs allow culture cells, manage fluid flow, and recreate biochemical and mechanical stimuli, with high reproducibility and low cost. Therefore, they offer a promising alternative to the traditional preclinical testing of pharmaceutical drugs, contributing to predict the efficacy of new developed drugs. Nevertheless, for this prediction is essential an accurate monitoring of cellular responses over time. However, the effective integration of various types of transducers-optical, electrochemical, mechanical, and resistive-into a single platform for real time monitoring remains a key challenge. This review explores the main transduction techniques used in OoCs, as well as current strategies, limitations, and suggests potential solutions for their integration into functional organ models.

Indexed as

Lab-On-A-Chip DevicesTransducersAnimalsHumansMicrophysiological SystemsTissue Engineeringintegrationmicrofabricationorgan‐on‐a‐chiptransducers

Identifiers

PMID41406360
PMCPMC12837388

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.