SynthesisJMIR mHealth and uHealth2025
Effectiveness of mHealth Interventions to Improve Follow-Up and Management Among Solid Organ Transplant Recipients: Systematic Review and Meta-Analysis.
Synthesis in JMIR mHealth and uHealth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Medication self-management during the developmental transition of responsibility among Chinese adolescent liver transplant recipients: a qualitative descriptive study.European journal of pediatrics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEffective follow-up and management after organ transplantation are crucial for transplant recipients. Mobile health (mHealth) interventions have emerged as a significant approach for facilitating follow-up and management. However, there is a lack of systematic reviews and meta-analyses of their effectiveness.
objectiveThis study aimed to systematically review and synthesize evidence regarding the effectiveness of mHealth interventions in enhancing follow-up and management for transplant recipients.
methodsThis study included both randomized controlled trials (RCTs) and nonrandomized studies of interventions (NRSIs) that compared the effects of mHealth interventions with usual care in transplant recipients by searching PubMed, Web of Science, Scopus, Embase, CINAHL, and CENTRAL from database inception to June 2025. The primary outcomes included self-care ability, medical regimen adherence, self-monitoring, communication and counseling, medication adherence, physical activity, nutrition, all-cause mortality, complications, rehospitalization, and emergency and outpatient department visits. The risk of bias for each study was assessed using version 2 of the Cochrane risk-of-bias tool for RCTs and the Risk of Bias in Nonrandomized Studies of Interventions tool for NRSIs. Data extraction and quality assessment were conducted by 2 reviewers independently. Data synthesis was conducted using Review Manager. Both a meta-analysis and a narrative synthesis were carried out.
resultsA total of 23 studies (n=15, 65% RCTs and n=8, 35% NRSIs) with 2022 transplant recipients were included. Compared to the control group, mHealth interventions significantly improved self-care ability (mean difference 14.49, 95% CI 9.61-19.36; P<.001) and reduced rehospitalization (odds ratio [OR] 0.49, 95% CI 0.34-0.71; P<.001). The meta-analysis demonstrated no statistically significant difference in mortality rates (OR 0.73, 95% CI 0.39-1.35; P=.31), rejection (OR 0.55, 95% CI 0.25-1.19; P=.13), or infection (OR 0.33, 95% CI 0.06-1.82; P=.20) between the mHealth intervention and control groups. The narrative synthesis indicated that mHealth interventions could effectively promote adherence to medical regimens and medications, facilitate self-monitoring, and improve communication and consultation.
conclusionsmHealth interventions significantly improved self-care ability and reduced rehospitalization rates among organ transplant recipients. However, these interventions did not demonstrate a significant effect on all-cause mortality or complications. mHealth interventions showed potential benefits for various self-management behaviors in organ transplant recipients, but these findings need to be further verified. Future research should prioritize high-quality studies that investigate the impact of mHealth on physical activity, nutrition, and other patient-centered outcomes.
trial registrationInternational Platform of Registered Systematic Review and Meta-Analysis Protocols INPLASY202480101; https://inplasy.com/inplasy-2024-8-0101/. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.37766/inplasy2024.8.0101.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.