ArticleCancer medicine2025
Can Surgical Approach and Postoperative Factors Impact Survival in Rectal Cancer? Robotic Versus Laparoscopic Insights.
Article in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Does Robotic Adrenalectomy Outperform Laparoscopic Approaches in Obese Patients? A Systematic Review and Subgroup Meta-Analysis of 1,107 Patients.The international journal of medical robotics + computer assisted surgery : MRCAS · 2026Pooled it
- Robotic versus laparoscopic versus open hepatectomy for hepatocellular carcinoma: a systematic review and network meta-analysis.Journal of robotic surgery · 2026Pooled it
- Can Surgical Approach and Postoperative Factors Impact Survival in Rectal Cancer? Robotic Versus Laparoscopic Insights.Cancer medicine · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to evaluate the long-term oncologic outcomes of robotic-assisted versus laparoscopic surgery in non-metastatic patients with locally advanced rectal cancer and to identify prognostic factors influencing overall survival (OS) and disease-free survival (DFS). MATERIAL AND
methodsIn this retrospective cohort study, 74 patients with mid or low rectal cancer underwent either laparoscopic (Gr. 1) (n = 28) or robotic-assisted (Gr. 2) (n = 46) surgery over 10 years. Baseline characteristics, surgical details, postoperative complications, and survival outcomes were analyzed. Multivariate Cox regression was used to identify independent predictors of OS and DFS.
resultsBoth groups had no significant difference in hospital stay, conversion rates, or postoperative complications. Multivariate analysis revealed that robotic surgery was independently associated with improved OS (HR: 2.651; p = 0.019). Other significant predictors of poor OS included tumor grade G3, perineural invasion, and postoperative complications. For DFS, perineural invasion, postoperative complications, conversion to open surgery, and tumor recurrence were associated with worse outcomes. Restoration of bowel continuity via end-to-end anastomosis was linked to improved survival.
conclusionsRobotic-assisted surgery offers comparable, and in some aspects superior, long-term oncologic outcomes to laparoscopic surgery for locally advanced rectal cancer. Independent predictors of poor survival included high-grade tumors, perineural invasion, conversion to open surgery, and postoperative complications. Surgical technique, selection criteria, and perioperative care remain crucial for optimizing outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.