Observational studyBMJ open respiratory research2025
Air pollution, inhaled therapy and COPD exacerbations in Yunlin, Taiwan: a 2016-2024 single-centre retrospective cohort with environmental and carbon-footprint analyses.
Observational study in BMJ open respiratory research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
3 authors.
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Abstract
backgroundAir pollution exacerbates chronic obstructive pulmonary disease (COPD), increasing hospitalisation and exacerbation rates. While inhaled therapy is a cornerstone of COPD management, pressurised metered-dose inhalers (pMDIs) significantly contribute to greenhouse gas (GHG) emissions. This study evaluates the interplay between air pollution exposure, inhaled therapy selection and COPD exacerbations to identify strategies that optimise clinical outcomes while reducing environmental impact.
methodsA retrospective observational cohort study was conducted using COPD patient records (ICD-10: J44.0, J44.1, J44.8, J44.9) from the National Taiwan University Hospital Yunlin Branch (2016-2024). Patient visits, including outpatient, emergency and inpatient admissions, were analysed alongside air pollution data (PM
resultsHigher PM
conclusionIn this single-centre retrospective study, higher ambient PM
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