Evidence map›Paper›PMID 41407765›Full record

ArticleScientific reports2025

Comprehensive Theoretical, Spectroscopic, Solvent, Topological and Antimicrobial investigation of 5-Chloro-6-fluoro-2-(2-pyrazinyl)-1H-benzimidazole.

Fasiuddin G S, A Aathif Basha, Attar Kubaib, Syed Khasim, Gassoumi Bouzid, Adnan Almasoudi, Mohammad Rehan Ajmal

Abstract read
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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fasiuddin G SDepartment of Physics, Government Thirumagal Mill's College (Affiliated To Thiruvalluvar University), Gudiyatham, Tamil Nadu, 635803, India.
A Aathif BashaDepartment of Physics, KNS Institute of Technology, (Affiliated to Visvesvaraya Technological University), Bangalore, Karnataka, 560064, India. aatifbasha@gmail.com.
Attar KubaibDepartment of Chemistry, Islamiah College (Autonomous), (Affiliated to Thiruvalluvar University), Vaniyambadi, Tamilnadu, 635752, India. attar.kubaib@gmail.com.
Syed KhasimAdvanced Materials Research Laboratory, Department of Physics, Faculty of Science, University of Tabuk, 71491, Tabuk, Saudi Arabia.
Gassoumi BouzidLaboratory of Advanced Materials and Interfaces (LIMA), Faculty of Sciences, Avenue of the environment, University of Monastir, 5019, Monastir, Tunisia.
Adnan AlmasoudiDepartment of Physics, Faculty of Science, University of Tabuk, 71491, Tabuk, Saudi Arabia.
Mohammad Rehan AjmalPhysical Biochemistry Research Laboratory, Biochemistry Department, Faculty of Science, University of Tabuk, 71491, Tabuk, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents comprehensive theoretical, spectroscopic, and biological investigations of the compound 5-Chloro-6-fluoro-2-(2-pyrazinyl)-1H-benzimidazole (5CF2PB). Density Functional Theory (DFT) calculations were performed at the B3LYP/6-311 +  + G(d,p) level, and a Potential Energy Scan (PES) was carried out to identify the most stable conformer and its optimized geometry. Theoretical vibrational frequencies and Potential Energy Distribution (PED) analysis were correlated with experimental FT-IR and FT-Raman spectra, showing excellent agreement. Experimental UV-Vis and

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsBenzimidazolesDensity Functional TheoryMicrobial Sensitivity TestsMolecular Docking SimulationSolventsSpectroscopy, Fourier Transform InfraredSpectrum Analysis, RamanAnti-Bacterial AgentsAnti-Infective AgentsBenzimidazolesSolventsIn vitro analysisMolecular dockingMolecular dynamicsSpectroscopic studiesTopological analysis

Identifiers

PMID41407765
PMCPMC12712073

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.