ReviewEuropean journal of medical research2025
Unveiling the metal-driven death: ferroptosis and cuproptosis in leukemia.
Review in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cuproptosis and prostate cancer: from molecular mechanisms and microenvironment remodeling to precision therapy.Frontiers in oncology · 2026Review
- Copper Homeostasis and Cuproptosis in Neurological Disorders.Drug design, development and therapy · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Cell death is essential for tumor cells and can occur due to damage or aging. Traditional concepts such as necrosis and apoptosis do not completely account for it. New forms, such as cuproptosis and ferroptosis, involve metal ion buildup and relate to cell metabolism, signaling, and drug resistance. These forms are particularly relevant in leukemia development. This review discusses the advancements in understanding the mechanisms of ferroptosis and cuproptosis and their impact on leukemia, opportunities and challenges in leukemia treatment are explored, emphasizing the potential therapeutic direction of ferroptosis and cuproptosis, to provide new theoretical basis and strategies for the treatment of clinical leukemia diseases.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.