ArticleScientific reports2025
Immunomodulatory, antioxidant, and growth-promoting properties of Avicennia marina leaf extract on Nile tilapia.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Effects of DietaryAnimals : an open access journal from MDPI · 2026Article
- Dietary co-supplementation of silymarin and stevioside enhances growth, immunity, and disease resistance in Nile tilapia.Veterinary research communications · 2026Article
- Dietary Matrine Supplementation Enhances Growth, Immunity and Disease Resistance in Nile Tilapia (Animals : an open access journal from MDPI · 2026Article
- Nutritional Impacts ofAquaculture nutrition · 2026Article
Corrections and comments
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Authors and funding
1 author.
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Abstract
This study evaluated the effects of Avicennia marina leaf aqueous extract on Nile tilapia performance. Fish (5.15 g, n = 675) were fed diets containing 0, 100, 200, 300, and 400 mg/kg extract for 60 days. Fish fed 200-300 mg/kg diets showed better growth status (P < 0.05), along with improved feed utilization. Digestive enzyme levels (amylase, lipase, protease) were better, and intestinal histomorphology was optimized, particularly at 200-300 mg/kg. Biochemical assessment of the serum indicated increased levels of total protein, albumin, and globulin, with reduced glucose, cholesterol, and cortisol in fish receiving 200-400 mg/kg. Hepatic antioxidants (SOD, CAT, GSH-Px) increased, while malondialdehyde (MDA) decreased. Immune responses (lysozyme, NBT reduction, Streptococcus agalactiae inhibition) were enhanced, and gene expression showed upregulated IGF-1, SOD, CAT, and GSH-Px with downregulated IL-1β and TNF-1α in the 200-400 mg/kg groups. Dietary A. marina extract at 200-300 mg/kg enhanced growth, digestive efficiency, antioxidant status, immune functions, and gene expression in Oreochromis niloticus, suggesting its promise as a natural feed additive in aquaculture.
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