ArticleSage open pediatrics
Kidney Injury Molecule-1 as Novel Marker of the Early Subclinical Kidney Injury in Children With Type 1 Diabetes Mellitus.
Article in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Kidney injury molecule-1 as a biomarker of diabetic kidney disease in children with type 1 diabetes: a systematic review and quantitative synthesis.Childhood kidney diseases · 2026Review
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Objective: To determine the anamnestic, clinical, laboratory, instrumental, and functional features in children with type 1 diabetes mellitus (T1D) and subclinical diabetic nephropathy (DN); to assess the diagnostic value of urinary KIM-1 levels. Methodology: The study involved 80 children aged 3 to 18 years with type 1 diabetes and/or diabetic nephropathy in compliance with ethical standards. All patients underwent a comprehensive clinical examination, and measurement of KIM-1 levels in urine. Results: In DN group the level of KIM-1 was significantly higher than inT1D group. In T1D group KIM-1 strongly correlated with T1D duration, number of DKA episodes/year. In DN group KIM-1 is strongly correlated with T1D duration, MAU and number of DKA episodes/year. T1D duration, MAU and disease status (T1D vs DN) were independent predictors of urinary KIM-1 levels. Conclusions: Urinary KIM-1 can be an early biomarker of kidney injury in pediatric patients with T1D, before overt clinical signs of DN.
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