ReviewFrontiers in public health2025
Addressing the challenge of tuberculosis screening in diabetic populations: a narrative review of methods and strategies.
Review in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The comorbidity of diabetes and tuberculosis (TB) poses a major public health challenge. Patients with diabetes have impaired immune function, increasing their risk of contracting TB. They often present with atypical clinical symptoms after infection, which can lead to delayed diagnosis. Therefore, TB screening in the diabetic patients is essential. This study systematically reviews advances in TB screening strategies for diabetic patients by searching databases including PubMed, WHO Global Index Medicus, Web of Science, China National Knowledge Infrastructure (CNKI), and Wanfang Data Knowledge Service Platform (search period: 2000-2025). We compare the efficacy of various screening techniques and strategies, discuss their suitable scenarios, advantages, and disadvantages, and provide recommendations for post-screening case management and cohort studies of screened populations. Our review found that novel screening technologies are gaining traction for TB screening in diabetes. AI-based imaging significantly improves the accuracy and efficiency of traditional radiological diagnosis. Oral swab testing and urine-based lipoarabinomannan (LAM) testing help overcome the challenge of specimen collection in individuals who have difficulty producing sputum. Recombinant fusion protein ESAT6-CPF10 (EC) skin test shows good accuracy and cost-effectiveness for latent tuberculosis infection (LTBI) screening. However, some techniques still require large-scale validation specifically in diabetic patients. The choice of TB screening strategy should consider local TB prevalence, prioritizing screening for high-risk subgroups among diabetic patients is cost-effective. The therapeutic management of patients with concurrent diabetes and tuberculosis is challenging. Successful treatment depends on the appropriate management of drug interactions, improved medication adherence, effective glycemic control, and timely drug susceptibility testing to adjust anti-TB regimens. Preventive treatment regimens for patients with diabetes and LTBI require further research. This study aims to provide evidence-based references for public health policymakers to help develop more targeted TB screening systems for diabetic patients, thereby improving early diagnosis and treatment rates, and reducing TB incidence and transmission risk.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.