Evidence map›Paper›PMID 41409782›Full record

ArticleSurgical oncology insight2025

HOXA13 overexpression is associated with poor prognosis in colorectal liver metastases

David G Su, Vadim Kurbatov, Xujun Wang, Zhaoshi Zeng, Philip B Paty, Caroline H Johnson, Jun Lu, Sajid A Khan

Abstract read
In one paragraph

Article in Surgical oncology insight, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David G SuDepartment of Surgery/Surgical Oncology, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA.
Vadim KurbatovDepartment of Surgery/Surgical Oncology, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA.
Xujun WangSJTU-Yale Joint Center for Biostatistics, School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Zhaoshi ZengDepartment of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA.
Philip B PatyDepartment of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA.
Caroline H JohnsonDepartment of Environmental Health Sciences, Yale School of Public Health, 60 College Street, New Haven, CT 06510, USA.
Jun LuDepartment of Genetics, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06378, USA.
Sajid A KhanDepartment of Surgery/Surgical Oncology, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
Yale Cancer Center Advanced Training Program for Physician-Scientists (YCC-ATPP)T32CA233414 · NCI · YALE UNIVERSITY · PI Eric P. Winer · 2019 to 2026
$3.2M
Understanding sex differences in colon cancer metabolismR21CA223686 · NCI · YALE UNIVERSITY · PI JOHNSON, CAROLINE HELEN, KHAN, SAJID A · 2018 to 2019
$394k
NCATS NIH HHS KL2 TR001862NCI NIH HHS P30 CA008748NCI NIH HHS R21 CA223686NCI NIH HHS T32 CA233414
6 · The paper itself

Abstract

Curative-intent hepatectomy in colorectal cancer liver metastasis (CRCLM) is guided by clinical criteria; however, molecular biomarkers may enhance prognostication. Homeobox (HOX) gene family is often dysregulated in cancer and may serve as a prognostic tool in metastatic colorectal cancer. Bulk RNA extraction was performed in frozen colorectal liver tumors (N = 39), and differentially expressed

Indexed as

Colorectal cancerHOX genesLiver metastasesTranscriptomics

Identifiers

PMID41409782
PMCPMC12707700

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.