ReviewInflammopharmacology2026
Valorisation of citrus peels: implications for cardiovascular diseases and diabetes management.
Review in Inflammopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Potential Involvement of PI3K/AKT Signaling Pathway in the Protective Effects ofAntioxidants (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Citrus peels, obtained from fruits belonging to the genus Citrus, of family Rutaceae, represents a major agro-industrial waste with significant nutritional and health benefits. These are composed of a variety of compounds, including flavonoids (hesperidin, naringin, quercetin, kaempferol), phenolic acids (caffeic acid, p-coumaric acid, ferulic acid, sinapic acid), essential oils, carbohydrates, amino acids and fatty acids, that can be extracted using green extraction techniques such as pulse electric field, enzyme-assisted extraction and so on. Emerging evidence highlights their numerous therapeutic benefits, including anti-diabetic, antioxidant, anti-inflammatory, anti-hyperlipidaemic and prebiotic effects. These therapeutic effects are provided through multiple pathways such as neutralising of reactive oxygen species, enhancing activity of antioxidant enzymes, suppression of inflammatory cytokines, regulation of blood pressure and blood glucose, lipid metabolism and modulation of gut microbiota. Despite the health-promising effects, existing findings rarely focus on in-vitro and in-vivo studies, primarily for antioxidant and anti-inflammatory activity. Considering the existing research gaps, this review attempts to highlight the significant potential of citrus peels, their nutritional and bioactive composition. Moreover, it examines the mechanism by which citrus peel bioactive compounds exert anti-diabetic and cardioprotective effects by reducing oxidative stress and inflammatory cytokines, with supporting in-vitro and in-vivo studies. In addition, this review investigates the synergistic effect of peels with other compounds, alongside their regulatory effects on lipid profile and gut microflora. Collectively, this review highlights the citrus peels-derived phytoconstituents as a sustainable, economic and environmentally friendly alternative for mitigation of cardiometabolic diseases including diabetes and cardiovascular disorders.
Indexed as
Identifiers
41410812What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.